OBJECTIVE To investigate the antibacterial potential of the polar and non-polar extracts of the seeds of Melia azedarach (M. azedarach) L. (Meliaceae) against eighteen hospital isolated human pathogenic bacterial strains. METHODS Petrol, benzene, ethyl acetate, methanol, and aqueous extracts at five different concentrations (1, 2, 5, 10 and 15 mg/mL) were evaluated. Disk diffusion method was ...

Antimicrobial efficiency of Melia azedarach L. a medicinal plants (leaf extracts) were examined using Methanol, Ethanol, Petroleum ether and water, as solvents and tested against eight human pathogens like Bacteria: Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Fungi: Aspergillus niger, Aspergillus flavus, Fusarium oxisporum, Rhizopus stolonifer using agar we...

Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 microM and 20 microM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods.

From the methanol extract of Penicillium sp. cultivated on sterilized rice for three weeks we isolated three new meroterpenes preaustinoid A1, A2 and B1. The fungus was isolated from the root bark of Melia azedarach after surface sterilization. The structures of these compounds were identified by intensive spectroscopic studies.

Macrophomina phaseolina (Tassi) Goid is a soil-borne fungal pathogen that causes root rot disease in more than 500 plant species but no registered fungicide is available for its control. The present study was carried out to investigate the antifungal activity of aqueous leaf extracts of Azadirachta indica A. Juss., Melia azedarach L. and Toona ciliata Roxb. (Meliaceae) against M. phaseolina. Aq...

A crude acetone extract and oil of ripe fruits from Melia azedarach L. were evaluated against the 2nd and 4th instar larvae of Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae). Both oil and extract exhibited highly significant growth inhibition at all concentrations tested, while the oil of M. azedarach recorded higher insecticidal activity against both instars than the crude extract. GC...

Plant derivatives possessing insect repellent and antifeedant properties could offer an alternative approach for managing crop pests and dealing with insect-transmitted diseases. This chapter summarizes results from studies on insecticidal effects of Melia azedarach extracts from Central Argentina. Extracts from different plant structures (green/ripe fruits, green/senescent leaves) and a variet...

The antiparasitic activity of the drupe extracts of Melia azedarach L. (Meliaceae) growing in Argentina was tested against a tapeworm and an earthworm, showing to be better against tapeworms than the standard piperazine phosphate, which is used in the treatment of Cestoda infections.

Due to the depletion of petroleum oil reserves and the environmental issues both, efforts have made to utilize the renewable resources in the polymer synthesis now-a-days. Among the different renewable resources seed oils of different plants pay considerable attraction due to its unique properties. Melia azedarach is a medium sized tree largely cultivated throughout the country as a shadow tree...