نتایج جستجو برای: melanocyte stimulating hormone
تعداد نتایج: 187749 فیلتر نتایج به سال:
Abstract The leptin-melanocortin pathway is playing a pivotal role for central body weight regulation. melanocortin 4 receptor (MC4R) essential to induce satiety after activation by the endogenous ligands α-/β-melanocyte-stimulating hormone. relevance of biased signaling exemplified an MC4R agonist, which has been approved treatment rare forms monogenic obesity. Here discussed as new option dev...
The objective of the present studies was to develop and validate a system for isolation, purification and extended culture of pigment-producing cells in alpaca skin (melanocytes) responsible for coat color and to determine the effect of alpha melanocyte stimulating hormone treatment on mRNA expression for the melanocortin 1 receptor, a key gene involved in coat color regulation in other species...
Using an indirect immunoperoxidase technique, we studied the location of alpha-melanocyte-stimulating hormone-like fibers and cell bodies in the cat diencephalon. In the thalamus, almost all the immunoreactive fibers were found in the midline region, whereas in the hypothalamus immunoreactive fibers were observed in the whole structure. The hypothalamus showed a higher density of both immunorea...
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