This study proposes a new method for removal of metal artifacts from megavoltage cone beam computed tomography (MVCBCT) and kilovoltage CT (kVCT) images. Both images were combined to obtain prior image, which was forward projected to obtain surrogate data and replace metal trace in the uncorrected kVCT image. The corrected image was then reconstructed through filtered back projection. A similar...

Objective(s): Taking advantage of high atomic number of gold nanoparticles (GNPs) in radiation dose absorbing, many in vitro and in vivo studies have been carried out on using them as radio-sensitizer. In spite of noticeable dose enhancement by GNPs at keV energies, using this energy range for radiotherapy of deep-seated tumors is outdated. The aim of the present work was to examine the effect ...

background: an effective method for management of large and bulky malignant tumors. this treatment modality is also known as specially fractionated radiation therapy (sfrt). in this treatment technique a grid block converted the open radiation field into a series of pencil beams. dosimetric characteristics of an external beam grid radiation field have been investigated using experimental and mo...

PURPOSE Megavoltage photon beams are typically used for therapy because of their skin sparing effect. However, a focused low-energy x-ray beam would also be skin sparing, and would have a higher dose concentration at the focal spot. Such a beam can be produced with polycapillary optics. MCNP5 was used to model dose profiles for a scanned focused beam, using measured beam parameters. The potenti...

Purpose: To study and compare the dose response curves of the new GafChromic EBT3 film for megavoltage and kilovoltage x-ray beams, with different spatial resolutions. Methods: EBT3 films (lot#A101711-02) were exposed to each x-ray beam (6 MV, 15 MV, and 50 kV) at 7 dose values (50 3200 cGy). Each film piece was scanned three consecutive times in the center of Epson 10000XL flatbed scanner in 4...

This study investigates the feasibility and applicability of cone beam CT for a megavoltage therapeutic LINAC. A Rando head phantom was irradiated using the 15 MV beam of a Varian 2100C LINAC at MSKCC for gantry angles from -102° to 102° with a 2° increment. The projection image for each gantry angle was obtained using a Varian Mark II EPID. Reference images without phantom were also collected ...