background and objective: microbial protein production can resolve one of the major world challenges, i.e. lack of protein sources. candida tropicalis growth was investigated to specify a medium to reach the highest cell proliferation and protein production. material and methods: fractional factorial design and the index of signal to noise ratio were applied for optimization of microbial protei...

Background: Cellulytic enzymes including carboxymethyl cellulases play the key role in hydrolysis of cellulose, a huge organic carbon reservoir on earth, into monomeric sugars and their eventual conversion into valuable chemicals and energy sources. Objectives: In this study, we described the identification of a basidiomycete isolate NDVN01 and optimization of culture conditions and medium com...

selected genotypes of sugar beet are often maintained by conventional propagation, but much faster rates of multiplication can be now obtained through micropropagation. on the other hand, plant micropropagation using bioreactors can decrease the cost of production and makes it an economical method. in this research, the possibility of using bioreactor and optimization of the tissue culture proc...

the culture media optimization is an inevitable part of upstream process development in therapeutic monoclonal antibodies (mabs) production. the quality by design (qbd) approach defines the assured quality of the final product through the development stage. an important step in qbd is determination of the main quality attributes. during the media optimization, some of the main quality attribute...

Marine actinomycetes were isolated from sediment samples collected from Pitchavaram mangrove ecosystem situated along the southeast coast of India. Maximum actinomycete population was noted in rhizosphere region. About 38% of the isolates produced L-asparaginase. One potential strain KUA106 produced higher level of enzyme using tryptone glucose yeast extract medium. Based on the studied phenoty...