نتایج جستجو برای: mechanical sensitivity

تعداد نتایج: 564908  

Journal: :Proceedings. Biological sciences 2017
Martha M Muñoz Philip S L Anderson S N Patek

The influence of biophysical relationships on rates of morphological evolution is a cornerstone of evolutionary theory. Mechanical sensitivity-the correlation strength between mechanical output and the system's underlying morphological components-is thought to impact the evolutionary dynamics of form-function relationships, yet has rarely been examined. Here, we compare the evolutionary rates o...

Journal: :The Journal of the Acoustical Society of America 1974

2015
Amanda H Lewis Jörg Grandl Richard Aldrich

Piezo1 ion channels mediate the conversion of mechanical forces into electrical signals and are critical for responsiveness to touch in metazoans. The apparent mechanical sensitivity of Piezo1 varies substantially across cellular environments, stimulating methods and protocols, raising the fundamental questions of what precise physical stimulus activates the channel and how its stimulus sensiti...

Journal: :Investigative ophthalmology & visual science 2011
Waldir Neira-Zalentein Juha M Holopainen Timo M T Tervo Fernando Borrás M Carmen Acosta Carlos Belmonte Juana Gallar

PURPOSE To determine the changes in corneal sensitivity to different stimulus modalities in diabetes mellitus (DM)1 and DM2 patients with retinopathy, and to explore whether argon laser photocoagulation exacerbates sensitivity loss in diabetic patients. METHODS Corneal sensitivity to different modalities of stimulus was determined in one randomized eye in 52 patients with DM1 (n = 35) or DM2 ...

One of the main milestones in the study of opto-mechanical system is to increase the sensitivity of weak forces measurement up to the standard quantum limit. We have studied the detection of weak force under a bistable condition in red detuned regime. In this case, dynamics of the system behaves asymptotically similar to stationary state and applying external force affects phase and fluctuation...

Journal: :Science 2017
Changgeng Peng Lili Li Ming-Dong Zhang Carolina Bengtsson Gonzales Marc Parisien Inna Belfer Dmitry Usoskin Hind Abdo Alessandro Furlan Martin Häring Francois Lallemend Tibor Harkany Luda Diatchenko Tomas Hökfelt Jens Hjerling-Leffler Patrik Ernfors

Nociception is protective and prevents tissue damage but can also facilitate chronic pain. Whether a general principle governs these two types of pain is unknown. Here, we show that both basal mechanical and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice. This single cluster controls more than 80% of neuropathic pain-regulated genes and scales basal mechanical sen...

This paper proposes a Micro-electro-mechanical (MEMS) capacitive pressure sensor that relies on the movable electrode displaced like a flat plate equal to the maximum center deflection of diaphragm. The diaphragm, movable electrode and mechanical coupling are made of polysilicon, gold and Si3N4, respectively. The fixed electrode is gold and the substrate is Pyrex glass. This proposed method inc...

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