Is a group best off if everyone co-operates? Theory often considers this to be so (e.g. the "conspiracy of doves"), this understanding underpinning social and economic policy. We observe, however, that after competition between "cheat" and "co-operator" strains of yeast, population fitness is maximized under co-existence. To address whether this might just be a peculiarity of our experimental s...

A method is presented for estimating the probability of an affected child being born to a clinically unaffected subject who is at risk for having inherited a rare gene for an autosomal dominant disorder of unknown penetrance. The maximal risk is 8.6% for children of persons at 50% risk for having inherited the mutant gene regardless of the true penetrance of the disorder in question. Applicatio...

biharmonic surfaces in euclidean space $mathbb{e}^3$ are firstly studied from a differential geometric point of view by bang-yen chen, who showed that the only biharmonic surfaces are minimal ones. a surface $x : m^2rightarrowmathbb{e}^{3}$ is called biharmonic if $delta^2x=0$, where $delta$ is the laplace operator of $m^2$. we study the $l_k$-biharmonic spacelike hypersurfaces in the $4$-dimen...

in this paper we show that if q is a power of a prime p , then the projective special linear group psl(2, q) and the stabilizer of a point of the projective line have maximum sum element orders among all proper subgroups of projective general linear group pgl(2, q) for q odd and even respectively

The authors present a method for decomposition of Bayesian networks into their maximal prime subgraphs. The correctness of the method is proven and results relating the maximal prime subgraph decomposition (MPD) to the maximal complete subgraphs of the moral graph of the original Bayesian network are presented. The maximal prime subgraphs of a Bayesian network can be organized as a tree which c...

BACKGROUND The European Society for Medical Oncology (ESMO) has developed the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS), a tool to assess the magnitude of clinical benefit from new cancer therapies. Grading is guided by a dual rule comparing the relative benefit (RB) and the absolute benefit (AB) achieved by the therapy to prespecified threshold values. The ESMO-MCBS v1.0 dual rule e...

We investigate the use of background knowledge ontology in ontology matching. We conducted experiments on matching two medical ontologies using third extensive one as background knowledge, and compare it to the direct match. Our results indicate that using background knowledge, in particular exploitation of its structure, has enormous benefit in the matching. The semantics of knowledge within t...