background: current treatments for joint diseases are moderately successful, but unfortunately are associated with significant side effects. this study was undertaken to investigate the combination effects of il-4 and prednisolone on tissue characteristics and production of matrix metalloproteinase-1(mmp-1) in il-lα-treated bovine nasal cartilage (bnc) explants. methods: bnc explants were cultu...

Advances in genomics and proteomics increasingly contribute to the understanding of signal transduction pathways that control growth, differentiation, and death of cells. Since defects in these processes may result in the expression of inherited and or acquired disease, the identification of candidate disease genes and modifier genes by parallel use of genotyping together with an integrated stu...