background: hemoglobin s arises is the result of a point mutation (a-t) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. the presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

We follow a research thread studying the predecessor problem on “smooth” distribution families. We propose a conceptually simpler solution utilizing wellknown results from much better studied variant of the problem that assumes nothing about the input. As a side effect, we are able to extend the range of handled input distributions for the most studied case needing expected O (log log n) time, ...

Perinatal maternal smoking exposure (PMSE) is one of the major environmental risk factors encountered by the fetus. PMSE is usually associated with adverse pregnancy outcomes that may manifest at different stages of life. Nevertheless, fetal growth restriction is the most common smoking-induced side effect. PMSE induces changes in the maternal multiple organ systems. These alterations may affec...

In this paper the known upper bound 10 for the number of Diophantine quintuples is reduced to 6.8·10. The key ingredient for the improvement is that certain individual bounds on parameters are now combined with a more efficient counting of tuples, and estimated by sums over divisor functions. As a side effect, we also improve the known upper bound 4 ·10 for the number of D(−1)-quadruples to 5 ·...

human serum albumin (hsa) is an abundant, multifunctional and nonglycosylated negatively charged plasma protein. hsa ascribed ligand-binding and transport properties, antioxidant functions and enzymatic activities. in the present study, the interaction and side effects of a new designed anti-cancer compound (1,10-phenanthroline butyl dithiocarbamato palladium(ii) nitrate) on hsa have been inves...

introduction: today, lasik surgery is one of the most common and effective procedures for correction of refractive errors. less than 1% of patients undergoing lasik operation suffer from serious and 3-5% suffers from mild complications. also, results of lasik in most centers are promising. with the recent inauguration of the lasik center of yazd, it was decided to evaluate the results and compl...

background & objectives: cryptorchidism is one of the most common congenital anomalies at birth. cryptorchidism is an abnormally positioned testis. the undescended testis can be located anywhere between the abdominal cavity and just outside the anatomical scrotum. this study was conducted to determine some etiologic factors in cryptorchidism. materials & methods: in an analytical cross-sectiona...

BACKGROUND The Indian Janani Suraksha Yojana (JSY) program is a demand-side program in which the state pays women a cash incentive to deliver in an institution, with the aim of reducing maternal mortality. The JSY has had 54 million beneficiaries since inception 7 years ago. Although a number of studies have demonstrated the effect of JSY on coverage, few have examined the direct impact of the ...

Using a household survey and regression methods, we assessed preferences for prescribed fire in the southern United States. We found that the majority of the respondents favored the use of prescribed fire. However, we observed pronounced racial variation in opinions on prescribed fire and its side effects. African Americans and Hispanics were less supportive and were more concerned about the si...

As a popular drug, suramin has attracted much attention for a century. It has an extensive record of clinical trials. This review article gives a brief introduction of its wide biological roles, remarkable pharmacological activities, and several side effects. Chemists and biological scientists have been working together for the design and synthesis of its derivatives and analogues. Some structu...