Hypothyroidism during pregnancy poses a challenge to the treating clinician. The diagnosis is made by a TSH that is greater than normal, and during pregnancy, this situation deserves therapy. Research over the years has shown that maternal thyroid hormones are very important in pregnancy. Importantly, emerging data seems to suggest that thyroid hormones are important for fetal brain development...

OBJECTIVE(S) Previous studies have shown that thyroid hormones are necessary for normal development of many organs and because of the importance of skin as the largest and the most important organ in human body protection in spite of external environment, the study of thyroid hormones effects on skin development is considerable. In this survey we have tried to study the effects of maternal hypo...

Dyshormonogenesis is an uncommon cause of congenital hypothyroidism. The most common abnormality is absent or insufficient thyroid peroxidase enzyme. Maternal intake of antithyroid drug can also lead to elevated thyroid stimulating hormone (TSH) in a neonate, albeit the scenario is temporary. We report one such interesting case where a clinically euthyroid neonate borne to a mother on antithyro...

OBJECTIVE To study the relation between maternal overt hypothyroidism and neurodevelopmental outcome of neonates in iodine-deficient region of Northern India (Kashmir Valley). DESIGN Prospective cohort study. SETTING Endocrinology department of a tertiary-care hospital. PARTICIPANTS 82 hypothyroid pregnant women were enrolled and followed up till delivery. The neonates born to this group ...

maternal iodine nutrition, and more recently, adequate maternal thyroid hormone is necessary during and after pregnancy to ensure the health of the mother and her offspring. Adequate maternal iodine nutrition must be maintained during pregnancy to meet the increased demand for thyroid hormone production that occurs with pregnancy. Maternal iodine supplies in the United States and in most of the...

Thyroid hormones are essential for brain development, and maternal thyroid disease may affect child neurocognitive development. Some types of seizures may also depend upon early exposure of the developing central nervous system, and we hypothesized that maternal thyroid dysfunction could increase the risk of seizure in the child. In a Danish population-based study we included 1,699,693 liveborn...

background: pregnancy has a huge impact on the thyroid function in both healthy women and those that have thyroid dysfunction. the prevalence of thyroid dysfunction in pregnant women is relatively high. objective: the objective of this review was to increase awareness and to provide a review on adverse effect of thyroid dysfunction including hyperthyroidism, hypothyroidism and thyroid autoimmun...

conclusions we revealed that thyroid dysfunction during pregnancy was associated with iugr and low apgar score even in subclinical forms. further studies are required to determine whether early diagnosis and treatment of thyroid diseases, even in subclinical form, can prevent their adverse effect on fetus. background maternal thyroid function alters during pregnancy. inadequate adaptation to th...