Longitudinal studies, where data are repeatedly collected on one subject over a period, are common in medical research. When effect of a time-varying exposure on an outcome of interest is measured at different time points, standard statistical methods fail to give robust estimate in the presence of time-dependent confounders. There is alternative method avoid, that is, inverse probability weigh...

A concept known as ‘marginal gains’, an approach to performance improvement in elite sport came to prominence during the London 2012 Olympics when Team GB cycling won a record eight gold medals. Since National Lottery funding was awarded in 1997 to develop British cycling, the ethos of making aggregated small gains in many areas to improve overall performance has been central to its success. Th...

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Abstract In this paper, we introduce the notion of a marginal tube, which is hypersurface foliated by surfaces. It generalises marginally trapped tube and several notions black hole horizons, for example trapping isolated dynamical etc. We prove that if every spacelike section surface, then null. There no assumption on topology tube. To it, study geometry surfaces in four-dimensional spacetime ...

statement of the problem: although all-ceramic restorations are broadly used, there is a lack of information concerning how their fit is affected by fabrication procedure and marginal configuration. purpose: the purpose of this study was to evaluate the marginal fit of zirconia cad/cam ceramic crowns before and after porcelain firing. the influence of finish line configuration on the marginal f...

purpose: the aim of this study was to evaluate the effect of two gingival finishing lines (90° shoulder and deep chamfer) on the marginal fitness of two types of full anatomic all-ceramic crowns; zirconia crowns (zikonzhan) and glass ceramic crowns (ips e-max cad) milled with cad/cam system. materials and methods: two dentoform teeth of left maxillary first molar were prepared with chamfer fini...

With the development of deregulated power systems and increase of prices in some hours of day and increase fuel price, demand response programs were noticed more by customers. demand response consists of a series of activities that governments or utilities design to change the amount or time of electric energy consumption, to achieve better social welfare or some times for maximizing the benefi...

It is well-known that a conditional independence statement for discrete variables is equivalent to constraining to zero a suitable set of log–linear interactions. In this paper we show that this is also equivalent to zero constraints on suitable sets of marginal log–linear interactions, that can be formulated within a class of smooth marginal log–linear models. This result allows much more flex...