Automated peripheral blood leukocyte differential counts (LDCs) are widely accepted in routine practice. However, many laboratories still reflexively perform manual LDCs based solely on abnormal automated results or instrument “flags,” before any manual triage step. We describe our transition to a procedure that uses manual methods to validate, rather than to replace, automated LDCs (an approac...

The exact delineation of chronic brain lesions is a crucial step when investigating the relationship between brain structure and (dys-)function. For this, manual tracing, although very time-consuming, is still the gold standard. In order to assess the possible contributions from other methods, we compared manual tracing of lesion boundaries with a newly developed semi-automated and a fully auto...

OBJECTIVE To evaluate the performance of 2 automated systems, Morpheus and Somnolyzer24X7, with various levels of human review/editing, in scoring polysomnographic (PSG) recordings from a clinical trial using zolpidem in a model of transient insomnia. METHODS 164 all-night PSG recordings from 82 subjects collected during 2 nights of sleep, one under placebo and one under zolpidem (10 mg) trea...

Currently, spermogram parameters are routine criteria for assessing male fertility. There two methods of semen analysis: traditional manual and automated. The concentration spermatozoa various motility categories is important in predicting physiological conception, as well choosing fertilization assisted reproductive technology programs. introduction automatic analyzers has shown that their use...

OBJECTIVES/HYPOTHESIS To verify the reliability and validity of automated scoring and compare it to that of manual scoring for diagnosing obstructive sleep apnea using an Embletta X100 level 2 portable device. STUDY DESIGN Retrospective study. METHODS A total of 116 patients with suspected obstructive sleep apnea who had successfully received portable polysomnography with the Embletta X100 ...