Despite very wide variations of malondialdehyde (MDA) concentrations in biological samples, it is still used as a biomarker of oxidative stress in clinical investigations. In the current perspective study, we aimed to summarize a number of critical analytical points for determination of MDA. Technical problems and controversial findings in healthy people and some psychiatric disorders reveal th...

INTRODUCTION The depletion of defensive body chemicals called antioxidants may increase the risk of complications from the most common form of diabetes mellitus. This study aims to evaluate blood serum lipid peroxidation product (malondialdehyde), an antioxidant, in non-insulin dependent male and female type 2 diabetic patients. METHODS Blood serum samples were collected from the diabetic pat...

The danger of lead in paint that is coated on the human body, silver can enter through skin and will interact with proteins, DNA, RNA oxidative stress. Formation Reactive Oxygen Species (ROS) by cause stress characterized an increase enzymes catalase, malondialdehyde (MDA) Oxidized glutathione (GSSG). aim this study was to analyze blood levels against Malondealdehyde humans Semarang City. This ...

Oxidative stress may play a central role in the onset of many diseases during the neonatal period. Malondialdehyde (MDA) is a marker of lipid peroxidation. The aim of this study was to evaluate a new marker, the malondialdehyde adduct to hemoglobin (MDA-Hb), which is measured in red blood cells (RBCs) and thus does not require that an additional blood sample be drawn. In this prospective study,...

Effects of melatonin on the levels of antioxidant enzymes including catalase (CAT), peroxidase (POD), glutathione reductase (GRd), and malondialdehyde (MDA), a lipid peroxidation marker, in erythrocytes of rainbow trout (Oncorhynchus mykiss) were investigated. The results showed that melatonin statistically activated the CAT, POD, and GRd activity (P < 0.05). Moreover, MDA levels were significa...

The malondialdehyde (MDA) contents in rat liver lysosomes increased in vitro by 400 nm ultraviolet light irradiation in the presence of hematoporphyrin (HP), but no changes were observed without HP. The MDA formation under the presence of HP was prevented by addition of vitamin E as antioxidant.

Serum malondialdehyde-like material (MDA-LM), as an index of lipid peroxidation, and the serum enzymes CK, CK-MB, LDH, LDH1 and, alpha-HBDH were evaluated in a group of 26 patients with acute myocardial infarction (AMI), seven with angina pectoris (AP), and in a normal control group of 94 subjects. MDA-LM values were within the normal range in AP patients, while in AMI patients a significant in...

BACKGROUND We have postulated that metabolic oxidation could be the source of signs and symptoms of hyperthyroidism. The present study was designed to evaluate urinary malondialdehyde levels in Graves' disease and compare this oxidative stress biomarker with the clinical evolution of patients suffering this illness. METHODS We evaluated the concentration of urinary and serum malondialdehyde (...