BACKGROUND The diagnosis of gastrointestinal stromal tumors is based on documentation of c-KIT and platelet-derived growth factor-alpha receptors or specific c-KIT mutations. Before the diagnosis of GIST was possible, all cases had been classified as sarcomas or benign tumors. OBJECTIVES To identify cases of GIST formerly diagnosed as abdominal or retroperitoneal mesenchymal tumors. METHODS...

Gastrointestinal Stromal Tumors (GIST) are the common mesenchymal tumors of gastrointestinal tract. They can display benign and malignant clinical behavior. The most common metastasis sites of malignant stromal tumor are liver, peritoneum, lung and bones. Metastasis to breast is extremely rare. Here, we present a case of GIST with liver, bone, lymph node and breast metastasis by reviewing the l...

Liposarcomas are malignant tumors of mesenchymal origin and one the most common human soft tissue sarcomas. Primary mediastinal liposarcomas, first mentioned in 1939, account for less than 1% all tumors, whereas primary liposarcomas approximately localizations. Mediastinal a heterogeneous group with different morphology, which often characterized by aggressive disease course leading to patient’...

conclusion our preliminary results have shown that although there is some overlap between benign and malignant tumors, adding dwi, mr imaging to routine soft tissue tumor protocols may improve diagnostic accuracy. results there was only one patient with a malignant cystic tumor and was not included in the statistical analysis. the median adc values of benign and malignant tumors were 2.31 ± 1.2...

Malignant peripheral nerve sheath tumors arise from Schwann cells or within existing neurofibromas and have a strong association with type 1 neurofibromatosis. These tumors are histologically diverse and may contain malignant areas of divergent mesenchymal differentiation, the most common of which is skeletal muscle (rhabdomyosarcoma). Malignant peripheral nerve sheath tumor with rhabdomyosarco...

Various tumors can occur in the scrotum. Of them, angiomyofibroblastoma-like tumors are very rare mesenchymal tumors. Angiomyofibroblastoma-like tumors cannot be easily differentially diagnosed from other malignant tumors invading the male genital tract on the basis of clinical characteristics and imaging study. Therefore, surgical removal and a histopathologic diagnosis must also be performed.

Phosphaturic mesenchymal tumors are rare neoplasms predominantly originating in the trunk and extremities. Malignant variants are exceedingly rare, and can present significant diagnostic challenges to the pathologist and otolaryngologist alike. This report describes the first case of malignant phosphaturic mesenchymal tumor involving the larynx, and emphasizes the importance of vigilance in bot...

Abstract BACKGROUND Despite advances in cancer diagnosis and clinical care, survival for many primary brain other central nervous system (CNS) tumors remain poor. This study performs a comprehensive analysis on these tumors. METHODS Survival differences were determined utilizing the National Program of Cancer Registries Analytic file all CNS Overall 5 most common histopathologies within specifi...

We describe a case of pulmonary blastoma, a rare primary lung malignancy which affects a younger population. This tumor contains both mesenchymal and epithelial elements. Pulmonary blastoma tends to relapse locally and metastasizes mainly in the first few years. It has a poor 5-year prognosis, and shows a potentid radio-chemosensitivity. Because these tumors are considered malignant, surgic...

Circumanal gland (CG) tumors are common neoplasms of older dogs. Of these, only circumanal carcinomas show clear metastatic potential, and even so metastases seem to be uncommon. Epithelial-mesenchymal transition (EMT) is a process that facilitates the initial steps metastasis, date it has not been systematically investigated in CG tumors. Insight into occurrence this would valuable asset under...