OBJECTIVES To evaluate patient outcome and investigate the prognostic factors of high-grade meningiomas by adopting the 2000 World Health Organization (WHO) classification system. METHODS Between 1986 and 2004, 74 patients were diagnosed with high-grade meningioma: 33 with atypical and 41 with anaplastic meningioma. The mean follow-up was 58.5 months. We reclassified all surgical specimens, a...

Meningiomas are common types of adult nerve system tumors. Although most cases are considered benign, due to its high rate of recurrence and easy malignant progression to anaplastic meningioma they present a puzzle for the current treatment. The HER-2 oncogene has important value for meningioma cells development and progression. So far, little is known about the effect on the exact underlying s...

Most meningiomas are benign; however anaplastic usually highly invasive and grow rapidly. These tumors can metastases outside the blood-brain barrier occurring to lungs. We present an unusual case of multiple pulmonary from recurrent intracranial meningioma in a 59-year-old male patient. Multiple very rare, but we should be aware this possibility patients with malignant especially, potential pr...

Meningiomas are frequent central nervous system neoplasms, which despite their predominant benignity, show sporadically malignant behavior. Type 2 neurofibromatosis and polymorphisms in several genes have been associated with meningioma risk and are probably involved in its pathogenesis. Although GWAS studies have found loci related to meningioma risk, little is known about the factors determin...

The false positive and false negative computed tomography diagnoses of meningioma made using EMI 1010 and 5005 machines on a consecutive series of patients seen over a period of four years are described. About 1.2% of intracranial meningiomas were not detected on initial CT scan, 6.6% were misdiagnosed including 5.2% which were thought to be malignant lesions; in 9.4% of the cases identified as...

DESCRIPTION A 65-year-old woman comes for headache management. Few years ago, she was diagnosed with a ‘single benign tumour of the anterior part of the brain’. A new contrast CT brain scan was done (figures 1 and 2); as she was claustrophobic, brain MRI was not ordered. The mass they have referred to was most likely a falcine meningioma. In addition, there is an oval hyperdense mass at the rig...

Meningioma rarely manifests as a subarachnoid hemorrhage (SAH), and invasion directly into a major intracranial artery is extremely rare. To the best of our knowledge, meningioma presenting with an SAH associated with major intracranial arterial invasion has never been reported. We present a case of sphenoid ridge meningotheliomatous meningioma manifesting as an SAH without pathologically atypi...

Most intracranial and intraspinal meningiomas are benign. Aggressive "malignant" behavior of intracranial meningiomas, with distant metastases usually to the lungs, has been well described [1-4]. We report a rare case of intraspinal meningioma with distant metastases to the lungs. Our review of the literature revealed only one other case of intraspinal meningioma with metastases to the lung [5].

Cranial malignant fibrous histiocytomas are rare tumors. Most are hypervascular, destructive masses that are similar to other malignant lesions and to malignant fibrous histiocytomas found elsewhere in the body. We describe a myxoid malignant fibrous histiocytoma of the temporal bone, possibly of dural origin, with features that more closely resembled a meningioma at CT, MR imaging, and angiogr...