background: thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. objective: to determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis b surface antibody (anti-hbs ab) following the last hbv vaccine injection. methods: this study was carried out on 215 thalassemic children who received t...

ßthalassemia is an inherited disorder of hemoglobin synthesis characterized by deficient synthesis of the ß-globin chain that causes severe anemia. Over the years, the combination of hypertransfusion and chelation therapy has significantly increased the survival of patients of ß-thalassemia. At the same time, there has been an increase in the frequency of complications, mainly caused by iron ov...

introduction: thalassemia is common in iran. appropriate therapy for this disease includes a regular blood transfusion and chelation therapy. however, patients will inevitably confront with side effects, particularly iron overloads in critical organ including heart, ductless glands and liver. this study tries to determine the prevalence of diabetes mellitus in transfusion dependent β thalassemi...

background: iran is a country located on the thalassemic belt of the globe. investigating such issues is of a greater significance in southern provinces of the country where the high prevalence of thalassemia has imposed high costs and mental pressure on families and the healthcare system. methods: in this cross-sectional study conducted in 2011 as a census, the data related to patients or dise...

The four principles of Western medical bioethics, i.e., autonomy, nonmaleficence, beneficence and justice, published by Beauchamps Childress in their seminal ‘Principles Biomedical Ethics’, are understood as universal. However, Non-Western governments argue that they refer to cultural contexts, neglecting specifics Non-Western, for instance Islamic, civilizations. This paper addresses the claim...

background: major -thalassemia is the most common monogenic known disorder in iran and about 15000 persons are af fected. the purpose of this study was to evaluate the prevalence of orofacial complications. methods: in this cross-sectional study during 2003-2004, 300 patients with major -thalassemia referring to 8 hospitals for routine examinations, blood infusion and treatment in cities of teh...

introduction: there have been many reports and papers on deficient, normal and high levels of copper in patients with thalassemia major. the aim of this study is to evaluate copper status in a series of more than 300 patients with thalassemia major and determine the degree of copper deficiency or excess. methods: three hundred and seventy patients with thalassemia major over 5 years of age were...