PURPOSE As previously reported, magnesium sulphate administered parenterally significantly increased an opioid antinociception in different kinds of pain. Since the typical form of magnesium salts are poorly and slowly absorbed from the gastrointestinal tract we examined whether their micronized form could increase opioids induced antinociception. METHODS In behavioural studies on rats morphi...

Reactive uptake coefficients for nitric acid onto size-selected (d(ve) = 102 and 233 nm) sodium chloride aerosols are determined for relative humidities (RH) between 85% and 10%. Both pure sodium chloride and sodium chloride mixed with magnesium chloride (X(Mg/Na) = 0.114, typical of sea salt) are studied. The aerosol is equilibrated with a carrier gas stream at the desired RH and then mixed wi...

Isolated axons from the squid, Dosidicus gigas, were internally perfused with potassium fluoride solutions. Membrane currents were measured following step changes of membrane potential in a voltage-clamp arrangement with external isosmotic solution changes in the order: potassium-free artificial seawater; potassium chloride; potassium chloride containing 10, 25, 40 or 50, mM calcium or magnesiu...

Urinary magnesium and pH are known to modulate urinary calcium excretion, but the mechanisms underlying these relationships are unknown. In this study, the data from 17 clinical trials in which urinary magnesium and pH were pharmacologically manipulated were analyzed, and it was found that the change in urinary calcium excretion is directly proportional to the change in magnesium excretion and ...

background: potassium citrate (k‑cit) is one of the medications widely used in patients with urolithiasis. however, in some cases with calcium oxalate (caox) urolithiasis, the significant response to alkaline therapy with k‑cit alone does not occur. there is scarce published data on the effect of magnesium chloride (mg‑cl2) on urolithiasis in pediatric patients. this study aimed to evaluate the...

Cardioprotective role of intravenous administration of magnesium chloride was evaluated in rabbits by biochemical and histopathological parameters. Myocardial damage was induced by injecting (i.v.) isoprenaline 1, 2.5, 5 and 7.5 mg/kg body weight of animal. There was a dose dependent increase in the activity of cardiac enzyme creatinine kinase CK (C Max). Maximal elevation of CK (C Max) was obs...

Needle-like o r b ranch-like a ragonite was prepared from sparingly dissoluble magnesium carbonate and calcium chloride aqueous solution. The morphology, particle size, and aspect ratio of the product were characterized with SEM. The polymorphs and crystal size were characterized with XRD. Comparing with calcium sulfate and sodium carbonate that were used in our previous study, a high reactant ...

Nickel compounds are recognized to cause nasal and lung cancers. Magnesium is an effective protector against nickel-induced carcinogenesis in vivo, although its mechanisms of protection remain elusive. The effects of magnesium carbonate on the cytotoxicity and genotoxicity induced by nickel subsulfide were examined with respect to the inhibition of cell proliferation, micronuclei formation, DNA...