نتایج جستجو برای: macrophage activation syndrome
تعداد نتایج: 1068365 فیلتر نتایج به سال:
Macrophage activation syndrome is a potentially life threatening phenomenon characterised by aggressive proliferation of macrophages and T lymphocytes leading to haemophagocytosis of other blood cells and multi organ failure. Here we present a very unusual combination of leptospirosis and scrub typhus infection leading to macrophage activation syndrome. Scrub typhus associated with macrophage a...
n engl j med 368;13 nejm.org march 28, 2013 1257 macrophage activation syndrome. In animals, high levels of interleukin-6 contribute to the triggering of this syndrome1; additional cytokines, including interferon-γ, interleukin-1, and interleukin-18, might be involved in maintaining and amplifying the inflammatory response.2 Indeed, interleukin-1 antagonism may be beneficial in a full-blown cas...
BACKGROUND Macrophage activation syndrome is described as a "clinical syndrome of hyperinflammation resulting in an uncontrolled and ineffective immune response" in the context of an autoinflammatory or rheumatic disease. Current associations of macrophage activation syndrome with autoimmune disease most notably include a host of rheumatological conditions and inflammatory bowel disease. Epidem...
Hemophagocytic syndrome (HPS), also known as hemophagocytic lymphohistiocytosis (HLH) encompasses an infrequent group of non-malignant, yet potentially life-threatening disorders caused by massive cytokine release from activated lymphocytes and macrophages (Filipovich, 2009; Henter et al., 1998, 2007; Janka et al., 1998; Janka, 2009). This multisystem inflammatory syndrome is associated with a ...
AIM This study aimed to evaluate the demographic, clinical, laboratory properties of patients with macrophage activation syndrome and treatment outcomes. MATERIAL AND METHODS The data of the patients who were diagnosed with macrophage activation syndrome secondary to systemic juvenile idiopathic arthritis between June 2013-May 2014 were evaluated by screening patient records. RESULTS Ten pa...
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