Single genomic loci are often related to specific cellular functions, genetic diseases, or pathogenic infections. Visualization of single genomic loci in live human cells is currently of great interest, yet it remains challenging. Here, we describe a strategy for live cell imaging of single genomic loci by combining transcription activator-like effectors (TALEs) with a quantum dot labelling tec...

In this demo and poster paper, we describe the concept and implementation of an ontology-based storyteller for fairy tales. Its main functions are (i) annotating the tales by extracting timeline information, characters and dialogues with corresponding emotions expressed in the utterances, (ii) populating an existing ontology for fairy tales with the previously extracted information and (iii) us...

Text and speech corpora for training a tale telling robot have been designed, recorded and annotated. The aim of these corpora is to study expressive storytelling behaviour, and to help in designing expressive prosodic and co-verbal variations for the artificial storyteller). A set of 89 children tales in French serves as a basis for this work. The tales annotation principles and scheme are des...

We describe here our ongoing research on modeling conceptual and narrative structure of fairytales by a computer system. In this paper we focus on the variations of fairytales based on Cinderella from all around the world. We analyzed twenty-three Japanese texts of Cinderella tales and modeled their conceptual and narrative structures using the notions of composition elements and motifs. We the...

Transcription activator-like effectors (TALEs) are proteins secreted by Xanthomonas bacteria to aid the infection of plant species. TALEs assist infections by binding to specific DNA sequences and activating the expression of host genes. Recent results show that TALE proteins consist of a central repeat domain, which determines the DNA targeting specificity and can be rapidly synthesized de nov...

the authors of this article aim to compare character types in persian oral folktales and hans christian andersen’s fairytales. for a better clarification of this topic, the authors address issues such as morality, character’s will, and the portrayal of women in these stories. this paper comes to the following conclusions: first, both the content and the characters in hans christian andersen’s t...

Transcription Activators-Like Effectors (TALEs) belong to a family of virulence proteins from the Xanthomonas genus of bacterial plant pathogens that are translocated into the plant cell. In the nucleus, TALEs act as transcription factors inducing the expression of susceptibility genes. A code for TALE-DNA binding specificity and high-resolution three-dimensional structures of TALE-DNA complexe...

a r t i c l e i n f o Background: Transcription activator-like effectors (TALEs) are effector proteins secreted by certain plant pathogenic bacteria when infecting their hosts. Upon translocation, TALEs bind via a well-deciphered recognition code to specific sequences in the promoter region of targeted host genes, thereby activating expression of those targeted genes. Gene activation induced by...

Are fairy tales outdated to a modernised 21st century society? In 1976, clinical psychologist Professor Bruno Bettelheim wrote a book examining the power and utility of fairy tales in childhood development. Forty years later, his work maintains its importance. Through a Freudian lens, Bettelheim examines the emotional and symbolic facets of traditional children’s fairy tales alongside contempor...