The majority of first-time angiography patients are without obstructive coronary artery disease (CAD). A blood gene expression score (GES) for obstructive CAD likelihood was validated in the PREDICT study, but its relation to major adverse cardiovascular events (MACE) and revascularization was not assessed. Patients (N = 1,160) were followed up for MACE and revascularization 1 year post-index a...

BACKGROUND Risk of recurrent cardiovascular events following an initial cardiovascular-related hospitalization remains high despite available interventions. Rates of cardiovascular events as well as associated health care resource utilization and costs are needed to assess the value of treatments. OBJECTIVE To quantify, in patients with previous hospitalization for acute coronary syndrome (AC...

There were 50 consecutive idiopathic thrombocytopenic purpura (ITP) adult patients (platelet count < 100 x 10(9)/L) grouped according to positivity or negativity of a solid-phase modified antigen capture enzyme-linked immunosorbent assay (ELISA) test (MACE) against glycoprotein IIb/IIIa (GPIIb/IIIa), Ib/IX, and IIa/IIIa. Observation started on the day of MACE assay and lasted at least 6 months....

Objective: The aim of this study was to assess heart rate (HR) responses to exercise in the prediction of the major adverse cardiovascular events (MACE) in patients with revascularization. Methods: We retrospectively analyzed 253 patients with successful revascularization and exercise treadmill test (ETT) 4 months later in asymptomatic status. MACE was defined as cardiac death, nonfatal myocard...

Teaching is enjoyable and rewarding in many ways, and I am excited by the opportunity toworkwith students throughout my future career. Mymain areas of interest are computer systems, including distributed systems, operating systems, cloud systems, and computer networking. One of themost interesting parts of teaching computer systems comes in unraveling the layers and abstractions of complex syst...

Distributed systems represent some of themost interesting and successful computing applications in use today, from web search and social networks, to data analytics and large-scalemachine learning, to loosely-coupled microservices, serverless lambdas, and the public cloud. However, it is notoriously diõcult to understand, troubleshoot, and enforce distributed systems behaviors, because unlike s...

BACKGROUND Many ST-segment elevation myocardial infarction (STEMI) patients have multivessel disease. There is still controversy in treatment strategy in STEMI patients with multivessel disease. We compared clinical outcomes of multivessel revascularization with infarct- related artery (IRA) revascularization in STEMI patients. METHODS The 1,644 STEMI patients with multivessel disease (1,106 ...

OBJECTIVE Emergency department (ED) patients hospitalised with a suspected infection have an increased risk for major adverse cardiovascular events (MACE). This study aims to identify independent predictors of MACE after hospital admission which could be used for identification of high-risk patients who may benefit from preventive strategies. SETTING Dutch tertiary care centre and urban hospi...

BACKGROUND Evidence suggests that high-dose statin pretreatment may reduce the risk of periprocedural myocardial infarction (PMI) and major adverse cardiac events (MACE) for certain patients; however, previous analyses have not considered patients with a history of statin maintenance treatment. In this meta-analysis of randomized controlled trials (RCTs), we reevaluated the efficacy of short-te...