The aim of this study was to verify whether Lycium barbarum polysaccharides inhibits proliferation and migration of BIU87 cells through Pi3K/AKT pathway. Different concentrations of Lycium barbarum polysaccharides were used to incubate with BIU87cells. LY-294002 and IGF-1 were used to inhibit and activate Pi3K/AKT pathway respectively. MTT were used to investigate the proliferation of BIU87cell...

In North American Lycium (Solanaceae), the evolution of gender dimorphism has been proposed as a means of restoring outcrossing after polyploidization causes the loss of self-incompatibility. Previous studies of this process in Lycium focused on comparisons between species that differ in ploidy. We examined intraspecific variation in floral morphology and DNA content in populations of L. califo...

Gender dimorphism and polyploidy are important evolutionary transitions that have evolved repeatedly in many plant families. We show that gender dimorphism in North American Lycium (Solanaceae) has evolved in polyploid, self-compatible taxa whose closest relatives are cosexual, self-incompatible diploids. This has occurred independently in South African Lycium. We present additional evidence fo...

Water is generally considered to be the major limiting factor for perennial shrub growth in the Mojave Desert, USA. However, the responses of active fine roots to soil moisture and microsite differed among Ambrosia dumosa, Ephedra nevadensis, Larrea tridentata, and Lycium pallidum, suggesting differences in root foraging strategies. Ambrosia and Ephedra had a positive linear relationship betwee...

The plant genus Lycium (Solanaceae) originated in the Americas and includes approximately 85 species that are distributed worldwide. The vast majority of Old World species occur in southern Africa and eastern Asia. In this study, we examine biogeographic relationships among Old World species using a phylogenetic approach coupled with molecular evolutionary analyses of the S-RNase self-incompati...

IRINA CAMELIA CHIŞ, DOINA BALTARU, ANCA DUMITROVICI, ANDREI COŞERIU, FLORINA VLAD, REMUS MOLDOVAN, ADRIANA MUREŞAN 1 Department of Physiology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Clinicilor St., No. 1, Cluj district, Zip code 400023, Cluj-Napoca, Romania, [email protected] 2 “Constantin Papilian” Military Emergency Hospital, G-ral Traian Mosoiu Str., No. 22, Cluj district, Z...

A study was undertaken to evaluate the hypoglycemic activity of polysaccharide extracted from Lycium barbarum (LBP). The various parameters studied included body weight (bw), fasting blood glucose levels (FBG), total cholesterol (TC) and triglyceride (TG) in diabetic and normal mice. LBP treatment (20, 40 mg/ kg body weight) for 28 days resulted in a significant decrease in the concentration of...

Two new compounds, named lyciumlignan D (1) and lyciumphenyl propanoid A (2), along with seven known compounds, were isolated from the root bark of Lycium chinense. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds 3-9 were isolated from this genus for the first time. In the in vitro...