Abstract The increased concentrations of greenhouse gases in the atmosphere create an increase Earth’s thermal energy, which is mainly stored ocean. Quantification rate ocean heat content (OHC) vital for understanding current and future climate Earth. Linear trend lines have been frequently used to quantify long-term rates change, but are inappropriate because they cannot capture nonlinearity t...

Vitamin D is a promising, though under-explored, potential modifiable risk factor for acute respiratory infections (ARIs). We sought to investigate the association of vitamin D status with ARI in a large, nationally-representative sample of non-institutionalized individuals from the United States. We analyzed 14,108 individuals over 16 years of age in the National Health and Nutrition Survey (N...

To determine the effect of membership of the Royal College of General Practitioners (RCGP) on recognition of depression, odds ratios, Lowess-smoothed plots, and regression models were produced for recognition rates in a representative sample of 20,818 patient contacts for members and non-members of the RCGP Membership of the RCGP did not appear to convey greater ability to discriminate between ...

Epidemiological control of coronavirus disease 2019 (COVID-19) is needed to estimate the infection period confirmed cases and identify potential cases. The present study, targeting for which time COVID-19 symptom onset was disclosed, aimed investigate relationship between intervals (day) from testing cycle threshold (CT) values real-time reverse transcription-polymerase chain reaction. Of cases...

The median absolute deviation (MAD) of each trait (principal component) was used to measure within-line variance, as it is less sensitive to non-normality than other measures of spread [67, 68]. However, plotting the raw MADs of each line against the line median tended to show a dependency of the MAD on the median (Figure S2). To correct for this dependency, the residuals of a local (lowess) re...

A basic question in analyzing cDNA microarray data is normalization. The purpose of normalization is to remove systematic bias in the observed expression values by establishing a normalization curve across the whole dynamic range. A proper normalization procedure ensures that the normalized intensity ratios provide meaningful measures of relative expression levels. We propose a two-way semi-lin...

Background: Neutrophil percentage to albumin ratio (NPAR) has been shown be correlated with the prognosis of various diseases. This study aimed explore effect NPAR on patients in coronary care units (CCU). Method: All data this were extracted from Medical Information Mart for Intensive Care III (MIMIC-III, version1.4) database. divided into four groups according their quartiles. The primary out...

Recent proposals for implementation of kernel based nonparametric curve estimators are seen to be faster than naive direct implementations by factors up into the hundreds. The main ideas behind two different approaches of this type are made clear. Careful speed comparisons in a variety of settings, and using a variety of machines and software is done. Various issues on computational accuracy an...