BACKGROUND To assess the activity of single agent vinorelbine in pretreated non Hodgkin's lymphoma. PATIENTS AND METHODS Twenty-three pretreated patients with non-Hodgkin's lymphoma (14 intermediate-high grade, nine low-grade) were treated with vinorelbine 30 mg/m2/week for six months or up to four doses after achieving CR. RESULTS Among 13 evaluable patients with intermediate-high grade ly...

Objective(s): To validate the reliability of nuclear medicine physicians in diagnosing lymphoma using positron emission tomography/computed tomography using 2-deoxy-2-[18F]fluoro-D-glucose (FDG-PET/CT) and to determine findings that reliably suggest lymphoma.Methods: Seventy patients suspected of having lymphoma using FDG-PET/CT were enrolled in this retrospective study. Two nuclear medicine ph...

Up to 40% of non-Hodgkin's lymphomas occur at extranodal sites. Most of these arise in the gastrointestinal tract with the stomach as the commonest location. However gastric lymphoma makes up only 2-8% of all gastric malignancies and so, although the incidence is reported to be rising, these are relatively rare tumours. A conservative estimate would suggest that only 600 gastric lymphomas are d...

In the Working Formulation (WF), non-Hodgkin's lymphomas (NHL) are grouped according to their clinical behavior. These disorders are listed as entities defined by morphology, phenotype, and cytogenetics in the proposed Revised European-American Classification of Lymphoid Neoplasms (REAL), the clinical relevance of which is still debated. We analyzed 670 NHL cases included in two randomized clin...

Ocular annexes lymphomas are malignancies which occur in the conjunctiva, eyelids, lacrimal gland and orbit. Ocular annexes lymphoma is primarily a disease of older adults, with a slight female preponderance. Most lymphomas are low-grade B-cell lymphomas, with marginal zone lymphoma being by far the most common type. Marginal zone lymphoma typically involves the ocular annexes primarily, wherea...

The standard management of low-grade lymphoma remains controversial. Long-term follow-up studies of patients treated with conventional regimens have shown that currently available treatments are not curative. New Treatment Approaches for Low-Grade Lymphoma Nucleoside Analogs—Newer chemotherapeutic agents, such as fludarabine (Fludara) and cladribine (2-chlorodeoxyadenosine [Leustatin]), have si...