Objective(s): In recent years, the application of radiopharmaceuticals in nuclear medicine has increased substantially. Following the diagnostic procedures performed in nuclear medicine departments, such as myocardial perfusion imaging, patients generally receive considerable doses of radiation. Normally, radiation-induced DNA damages are expected following exposure to a low-dose ionizing radia...

in order to avoid using cytotoxic drugs and to minimize prednisolone side effects in frequent relapsing or steroid-dependent idiopathic nephrotic syndrome, 35 patients, 3 to 15 (mean= 8.1) years of age, were studied. while in remission for at least 6 weeks, the dose of prednisolone was reduced to 0.1-0.37 (mean= 0.23) mg/kg/day as a single dose for 12 to 72 (mean= 27.6) months. it was followed ...

background: the specific antibody response against newcastle disease virus (ndv) in the blood serum of chickens hatched from eggs exposed to low dose gamma-radiation was studied. materials and methods: two groups of eggs of commercial meat chicken lines were irradiated with the dose of 0.30 gy 60co gamma-rays before incubation and on the 19th day of incubation, respectively. the same number of ...

abstract a field experiment was conducted at plant pest and disease research institute in karaj,iran in 2005-2006 to determine the effect of low herbicide dose of clodinafop-propargyl on percentage of wild oat control, yield and economic return of wheat. the experiment included 2 wheat varieties (rooshan and niknejad (less and more competitiveness cultivar, respectively, 4 wild oat densities (0...

background: study of vascular and its secretory profile changes is an important issue in pathogenesis of radiation myelopathy. this paper reports the prostacyclin concentration changes after low-moderate doses of x-irradiation within a short period of time. materials and methods: cervical cords of wistar rats were irradiated to doses of 0.5, 1, 2, 4 and 6 gy x-rays. after 24 hours, 2 and 13 wee...

Human pluripotent stem cells will likely be a significant part of the regenerative medicine-driven healthcare revolution. In order to realize this potential, culture processes must be standardized, scalable and able to produce clinically relevant cell numbers, whilst maintaining critical biological functionality. This review comprises a broad overview of important bioprocess considerations, ref...

The concept of hormesis, or low-dose U-shaped responses, is now well established in toxicology and pharmacology but requires development in medicine and therapeutics. In doing so, care must be taken to not confuse metaphorical and chemical uses of the term hormesis. Low dose, continuous adaptive responses are fundamentally different than conventional pharmacology, and they may improve the scien...