نتایج جستجو برای: lonicera japonica thunb
تعداد نتایج: 10403 فیلتر نتایج به سال:
Lonicera japonica THUNB., which abundantly contains polyphenols, has been used as a traditional medicine for thousands of years in East Asian countries because of the anti-inflammation properties. This study aimed to investigate the anti-inflammatory mechanism of polyphenol components isolated from Korea L. japonica T. by nuclear factor-kappaB (NF-κB) and mitogen-activated protein kinases (MAPK...
A previous study showed that the contents of caffeoylquinic acids and iridoids, the major bioactive components in the postharvest Lonicera japonica Thunb., were induced by enhanced ultraviolet (UV)-A or UV-B irradiation. To clarify the UV-responsive key enzymes in the bioactive metabolites biosynthetic pathway and the related plant defense mechanism in L. japonica, 2DE in combination with MALDI...
Abstract We have purified a novel caffeoylquinic acid named 3,4-di- O -caffeoylquinic isobutyl ester from the flower buds of Lonicera japonica Thunb., Caprifoliaceae. However, biological function is still unknown. Here, we found that effectively inhibited proliferation and migration hepatocellular carcinoma cells, it displayed less toxicity to normal liver cell line. Mechanistic studies showed ...
Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone or in combination with peginterferon-α plus ribavirin. However, sustained viral responses vary in d...
BACKGROUND Lonicera japonica Thunb. is a plant used in traditional Chinese medicine known for its anti-inflammatory, anti-oxidative, anti-carcinogenic, and antiviral pharmacological properties. The major active secondary metabolites of this plant are chlorogenic acid (CGA) and luteoloside. While the biosynthetic pathways of these metabolites are relatively well known, the genetic information av...
Nonalcoholic steatohepatitis (NASH) is characterized as fat accumulation in the hepatic tissue associated with various degrees of inflammation and progressive fibrosis. The potent anti-inflammatory and ethnopharmacological properties of Lonicera japonica Thunb. (Caprifoliaceae) make it an excellent source of novel medicinal targets for the treatment of NASH. The aim of the study was to investig...
Flos Lonicerae, a widely used Vietnamese medicinal material, is the dried buds or flowers of Lonicera japonica Thunb., and several other species genus such as dasystyla Rehd., confusa DC., cambodiana Pierre ex Danguy, belonging to family Caprifoliaceae. This material has been for long time in traditional medicine clearing heat, removing toxins, dispersing wind heat. According variety recent phy...
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