background: the canonical wnt signal transduction (or the wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. beta-catenin is the central component of this signaling pathway. the activation of wnt/β-catenin signaling results in the cytoplasmic and nuclear accumulation of β-catenin. in the nucleus, β-catenin interacts with the tcf/lef transcription fa...

This study is to investigate the short- and long-run causal relationship between agglomeration (localization and urbanization) economies and labor productivity in the manufacturing sector of 28 Iranian provinces over an 11-year period, 2001–2011. Fully Modified Ordinary Least Squares (FMOLS) method was used to estimate our long-run panel data model. The empirical findings suggested that localiz...

Semi-solid materials undergo strain localization and shear band formation as a result of granular nature of semi-solid deformation. In the present study, to analyze the shear localization, a unified viscoplastic constitutive model was developed for the homogeneous flow. Then, a linearized analysis of the stability performed by examining the necessary condition for the perturbation growth. For t...

in this paper, a higher order continuum model is presented based on the cosserat continuum theory in 3d numerical simulation of shear band localization. as the classical continuum models suffer from the pathological mesh-dependence in strain softening models, the governing equations are regularized by adding the rotational degrees-of-freedom to conventional degrees-of-freedom. the fundamental r...

 Background: Bilateral neck exploration is the gold standard for parathyroid adenoma localization in primary hyperparathyroidism. But surgeons do not have adequate experience for accurate surgical exploration and new methods are developed for surgery like unilateral exploration and minimally invasive surgery, thus, preoperative localization could reduces time and stress in surgical performance....

In ‎the present ‎paper, ‎we ‎introduce the ‎two-wavelet ‎localization ‎operator ‎for ‎the square ‎integrable ‎representation ‎of a‎ ‎homogeneous space‎ with respect to a relatively invariant measure. ‎We show that it is a bounded linear operator. We investigate ‎some ‎properties ‎of the ‎two-wavelet ‎localization ‎operator ‎and ‎show ‎that ‎it ‎is a‎ ‎compact ‎operator ‎and is ‎contained ‎in‎ a...

Objective(s): Controversy exists about the localization of non-palpable breast lesions. In many countries, the gold standard for the diagnosis of these lesions is needle localization due to its accuracy. This study sought to compare the ultrasoundand radio-guided occult lesion localization (ROLL) as a simple method with the conventional procedures in terms of their diagnostic power. Methods: Th...

the association of secreted frizzled related protein type 4 (sfrp4) as an antagonist of wnt mole-cules in apoptotic events has been reported previously. moreover, its increased expression has been reported in the ovary of women with polycystic ovary (pco). we have demonstrated in-creased sfrp4 in pco-induced rat ovary related to an increased number of apoptotic follicles showing nuclear ?cateni...