_Background:_ Asthma is an airway disorder where inflammatory cytokines are partly responsible for exacerbating the disease. Interleukin (IL)-32, generally referred to as natural killer cell (NK4) transcript 4, described immunoregulator involved in stimulation of anti-/pro-inflammatory cytokines. The abnormal presence IL-32 has been observed during diseases, particularly asthma. This study aims...

It has been previously reported that amiloride suppresses inflammatory cytokine biosynthesis. However, the molecular mechanism involved has yet to be ascertained. Therefore, the immunoregulatory potential mediated by amiloride and the underlying signaling transduction pathway was investigated. Exposure of alveolar epithelial cells to amiloride or its analog, 5-( N,N -hexamethylene)-amiloride (H...

Tim-3 is a negative immunoregulator in anti-tumor response, but its mechanism chronic lymphocytic leukemia (CLL) not yet clear. The aim of this study was to understand the role Galectin-9/Tim-3 signaling pathway regulation CD4+ T cell subsets CLL patients. Flow cytometry results showed that number Treg cells obviously increased, and there significant Treg/Th17 imbalance In addition, overexpress...

Eucalyptol (1,8-cineole) compound contained in eucalyptus oil has the potential to inhibit viral infection pathways, as an antimicrobial and immunoregulator. Therefore, development of oil-based effervescent health drinks is urgently needed relieve symptoms being infected a virus during this pandemic. However, volatility quite high, so nano-based encapsulation method slow release these volatile ...