Objective(s): Production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. The goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. Materials and Methods: Multiple amino acid sequences of different i...

FRAP (Pederson, 2001 [this issue of Cell]). While it is easy to see dynamics of large structures like the nuclear envelope and classical nuclear organelles such as the nucleolus, what is remarkable about current FRAP meth-odologies is that they enable the dynamics of even the The Living Nucleus at San Antonio The potential instability of nuclear architecture during 7703 Floyd Curl Drive the cel...

one of the most important measures, in order to increase animal products and reduce imports, is the industrialization of animal husbandry units, specially the dairy cattle. the condition of milk production would be improved by this industrialization, which is in the direction of increasing the efficiency of milk production units. the purpose of this study is calculate , the efficiency of the tr...

Background: Many elderly individuals complain of difficulty in understanding speech in noise despite having normal hearing thresholds. According to previous studies, auditory training leads to improvement in speech-in-noise perception, but these studies did not consider the etiology, so their results cannot be generalized. The present study aimed at investigating the effectiveness of envelope-b...

In this paper a two-phase supply modulator suitable for envelope tracking power amplifier is presented. The designed supply modulator has the linear assisted switching architecture. Two-phase architecture is used in order to reduce the output switching ripples. The proposed architecture uses hysteretic control instead of pulse width modulation (PWM) which significantly reduces the circuit compl...

A series of cyclodextrin-based glycoconjugates, including glycoclusters and star glycopolymers, were synthesized via combination of CuAAC Huisgen coupling and copper-mediated living radical polymerization. These glycoconjugates showed high affinity binding to the human transmembrane lectin DC-SIGN and act as inhibitors to prevent the binding of HIV envelope protein gp120 to DC-SIGN at nanomolar...

Mitosis in free-living dinoflagellates is unusual in that the nuclear envelope remains intact but a number of cytoplasmic channels containing mi-crotubules run completely through the nucleus (8, 9, 13). The chromosomes are known to be attached to the nuclear envelope (1, 8, 13) and during division this connection appears to take the form of a narrow stalk of chromosome material which fits into ...

background: dengue is a global arboviral threat to humans; causing 390 million infections per year. the availability of safe and effective tetravalent dengue vaccine is a global requirement to prevent epidemics, morbidity, and mortality associated with it. methods: five experimental groups (6 mice per group) each of 5-week-old balb/c mice were immunized with vaccine and placebo (empty plasmid) ...

The Targeting Protein for Xklp2 (TPX2) is a central regulator of spindle assembly in vertebrate cells. The absence or excess of TPX2 inhibits spindle formation. We have defined a TPX2 signature motif that is present once in vertebrate sequences but twice in plants. Plant TPX2 is predominantly nuclear during interphase and is actively exported before nuclear envelope breakdown to initiate prospi...