objective: this study investigated tissue damages induced by chronic subcutaneous administration of nano- and microparticles of manganese dioxide (mno2) on the liver, kidneys and testes of rats. methods: rats (n=210) were divided into three groups: control, mno2 nanoparticle injected and mno2 microparticle injected. the experimental groups received subcutaneous injections with either nano- or m...

at first, in order to define acute toxicity of diazinon insecticide and butachlor herbicide, acute toxicity tests (lc5096h) were done, based on standard method (1989) o.e.c.d. in static way and for 96 hours. and the amount of acute toxicity (lc5096h) of diazinon and butachlor in 1 to 2 gram vimba vimba persa fry larva was determined to be 0.09 and 0.61 respectively. in order to do histology stu...

chlorotoxin is a 36 amino acids peptide, which is able to block chloride channels isolated from mouse brain. a derivative of chlorotoxin is synthesized and it is labeled by iodine 131; then animal experiments carry out on rats. multiple organ doses may be calculated with biological distribution results in rats with labeled compounds using simulated mcnp4c code. human dose can be calculated usin...

the present study was carried out in 2011 to measure concentration of heavy metals chromium and tin in liver and muscle tissue of liza aurata (golden grey mullet) in estuaries of the rivers babolroud, tajan and gorganroud. accordingly, after sampling the target are asandisolating muscle (18samples) and liver (18samples) tissues, they were digested and analyzed using graphite furnace atomic abso...

background: aspartate transaminase (ast) is an important enzyme in parasite and liver tissue. the purpose of this investigation is to evaluate triclabendazole (tcbz) effect on ast activity of fasciola gigantica parasite. to compare of enzyme level of parasite and its host tissue, enzyme activity of f. gigantica parasite and liver tissues were also determined. method: the livers were collected f...

conclusions in conclusion, at measurement can be beneficial for the safety or recovery of malathion-induced toxic injury in liver tissue and liver mitochondria. results in liver tissue, the activity of lpo and cat was higher in the malathion group in comparison to controls. at reduced malathion-induced lpo, sod, cat, and gpx in rat liver. coadministration of at with malathion improved lpo, sod,...

Bioaccumulation of heavy metals including Cd, Pb, Cu and Zn in muscle, gill, liver, kidney and stomach in Acipencer persicus was studied. Fish were collected from the ‘Iranian fishery zone 1’ located between Astara and Kiyahshahr. Samples (n=25) were collected from five stations in the study area during the autumn catch season in 2001. Samples were analyzed by wet digestion with hydrogen peroxi...