conclusion in breast cancer after nac, the lesion t2 relaxation time was reduced in the responders, and this finding is potentially useful to assess the response to nac. results in 26 cases with nac, the mean lesion t2 relaxation time before nac was 81.34 ± 13.68 ms, compared with 64.50 ± 8.71 ms after nac. significant differences in the lesion t2 relaxation times existed between the pre- and p...

Objectives We aim to explore and analyze the related influencing factors of liver cardiac iron overload in MDS patients detected by magnetic resonance imaging (MRI).Methods have T2* MRI 105 patients. Among them, 20 accepted examination before after chelation therapy (ICT). Results: found that adjusted ferritin (ASF) was significantly correlated with T2*. RBC transfusion volume, brain natriureti...

In this paper, we demonstrate the tunable T1 and T2 contrast abilities of engineered iron oxide nanoparticles with high performance for liver contrast-enhanced magnetic resonance imaging (MRI) in mice. To enhance the diagnostic accuracy of MRI, large numbers of contrast agents with T1 or T2 contrast ability have been widely explored. The comprehensive investigation of high-performance MRI contr...

OBJECTIVE To evaluate magnetic resonance imaging (MRI) parameters T2 signal, contrast enhancement (CE), and relative liver enhancement (RLE) of extracellular gadolinium-based contrast agent (GBCA)-enhanced MRI as a marker for hepatic fibrosis and inflammation in patients with primary sclerosing cholangitis (PSC). METHODS 3.0-Tesla MRI scans and liver biopsies of 40 patients (41.2 ± 17.1 years...

BACKGROUND Beta-thalassemia major (β-TM) patients need blood transfusions, which result in iron deposition. To regulate chelation therapy, iron load has to be measured. With MRI, the amount of signal loss and T2* decay time shortening are used for iron quantification. OBJECTIVES The aim was to measure adrenal iron load with T2* relaxometry using MRI, and to compare it with liver and cardiac i...

We studied the utility of pancreatic magnetic resonance imaging (MRI) in 72 thalassemia major patients (21 diabetic, 51 normoglycemic). Diabetic patients were significantly older (p<0.0001) and had smaller pancreas volume (p<0.0001). The two groups were comparable for ferritin and MRI-T2* heart, liver and pancreas. Pancreatic T2* signals were abnormal in 80% of both groups, and correlated with ...

Introduction Fatty infiltration of the liver is one of the primary features of nonalcoholic fatty liver disease. Therefore, accurate quantification of the liver fat content is an important factor in detecting hepatic diseases. MRI is an efficient noninvasive tool for assessing liver fat content. A commonly used liver fat quantification technique with MRI is a dual echo imaging (two gradient seq...