Lithium is widely used in medicine as an anti-depressive drug. In spite of abundant literature, questions on the side effects of lithium ions are far from being answered. In this study, the effects of lithium on biochemical parameters related to lipid metabolism were investigated. Male Wistar rats were treated with different doses of lithium for a period of up to 60 days. Blood samples were col...

lithium is widely used in medicine as an anti-depressive drug. in spite of abundant literature, questions on the side effects of lithium ions are far from being answered. in this study, the effects of lithium on biochemical parameters related to lipid metabolism were investigated. male wistar rats were treated with different doses of lithium for a period of up to 60 days. blood samples were col...

these experiments examined the effects of pre-test intra dorsal hippocampus (intra-ca1) administration of gabaa receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. male nmri mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received ip injections of either saline (10 ml/kg...

objective(s) it is believed that the mesenchymal stem cell (msc) differentiation and proliferation are the results of activation of wnt signaling pathway. on the other hand, lithium chloride is reported to be able to activate this pathway. the objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived msc. materials and ...

objective: the influence of cholinergic drugs on lithium-induced statedependent learning has been investigated in adult male mice. method: a single-trial step-down inhibitory avoidance task was selected. the drugs used in the study were lithium chloride physostigmine , nicotine hydrogen tartrate and scopolamine hydrobromide, atropine sulphate. the drugs were administrated through the peritoneal...

the effect of neuroloptics. carbamacepine and hensmliacepines in treatment of 8.3 patients with acute mania was studied. according to drug types. patients were divided into 5 groups: 1) lithium combined with ilubupridol. 2) lithium combined with one plxenoshiacine 3) lithium combined with two phenothiazines. 4) lithium combined with cubumazepine and 5) lithium combined with benzxliazepines no s...

in the present study, the interactions of three different lithium species li+, li3+ and ch3li with several different sites of the most stable tautomers of dna nucleo-bases are presented. this investigation is based on the results of thermochemical properties, quantum theory of atoms in molecules (qtaim) and natural bond orbital (nbo) analysis, obtained at b3lyp/6-311++g(d,p) level of theory. th...

These experiments examined the effects of pre-test intra dorsal hippocampus (intra-CA1) administration of GABAA receptor agonist and antagonist, muscimol and bicuculline respectively, on state-dependent learning induced by lithium. Male NMRI mice were trained in a one-trial step-down inhibitory avoidance task, and immediately after training they received IP injections of either saline (10 mL/kg...

background: b cell cll/lymphoma 2 protein, bcl-2, is an important anti-apoptotic factor that has been implicated in lithium’s neuroprotective effect. however, most studies have focused on assessing the effects of lithium in neurons, ignoring examination of bcl-2 in astrocytes, which also influence neuronal survival and are affected in bipolar disorder. the aim of this study was to evaluate whet...

data show that Greiner lithium-heparin tubes produce a frequency of duplicate errors similar to the frequency of errors obtained with the BD tubes. From the data obtained, use of the modified Modular P IFCC method substantially reduced but did not totally eliminate duplicate errors. For many years, we have observed on an intermittent basis duplicate errors when using lithium-heparin gel tubes (...