The statistical models of discrimination we covered previously were static models. In contrast, Altonji and Pierret (2001) use a dynamic model of employer learning to develop a test of statistical discrimination by firms. The theoretical underpinnings of their paper build closely on the paper by Farber and Gibbons (1996). Before discussing Altonji and Pierret (2001), we are first going to walk ...

This report presents a demonstration of ceramidase activity in the nuclear membrane or envelope of mammalian livers. The products of ceramidase reaction were identified by means of TLC for released fatty acid and HPLC for sphingosine. The ceramidase activity was maximum over a broad neutral to alkaline region ranging from pH 7.0 to 8.8. This activity was inhibited by N-oleoylethanolamine known ...

Abstract. We introduce and study a canonical quadratic form, called the torsion quadratic form, of the determinant line of a flat vector bundle over a closed oriented odd-dimensional manifold. This quadratic form caries less information than the refined analytic torsion, introduced in our previous work, but is easier to construct and closer related to the combinatorial Farber-Turaev torsion. In...

Harvard Medical School, Boston, Massachusetts Department of Neurosurgery, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Pathology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts York Hospital Oncology, York, Maine Department of Medical Oncology, Dana-Farber/Brigham & Women’s Cancer Center, Boston, Massachusetts Department of Radiation Oncol...

1 Van Vooren JP, Turneer M, Yernault JC, Dc Bruyn J, Burton E, Legros F, Farber CM. A multidot finmunobinding assay for the serodiagnosis oftuberculosis. Comparison with ELISA technique. J Immunol Methods 1988; 113:45-49 2 Van %boren JP, Farber CM, Motte 5, De Bruyn J, Legros F, Yernault JC. Assay of specific antibody response to myobacterial antigen for the diagnosis of a pleural effusion in a...

A formal National Cancer Institute Clinical Trials Cooperative Group Program was conceived in 1955 when Dr. Sidney Farber, Mary Lasker, and others approached Congress with a proposal to increase support for studies of chemotherapy of cancer. In response, Congress awarded US $5 million to the National Cancer Institute to establish the Chemotherapy National Service Center. The founders of the Can...

1 Institut de Recherches Interdisciplinaires en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, 6041-Gosselies, Belgium 2 Institut de Biologie et de Médecine Moléculaires, Université Libre de Bruxelles, 6041-Gosselies, Belgium 3 Laboratoire d’Histologie, de Neuroanatomie et de Neuropathologie, Université Libre de Bruxelles, 1070-Bruxelles, Belgium 4 Laboratoire de Neuropathologi...

Acid ceramidase (aCDase) is one of several enzymes responsible for ceramide degradation within mammalian cells. As such, aCDase regulates the intracellular levels of the bioactive lipid ceramide. An inherited deficiency of aCDase activity results in Farber disease (FD), also called lipogranulomatosis, which is characterized by ceramide accumulation in the tissues of patients. Diagnosis of FD is...

» This represents a truly significant advancement in the study of this disorder. « Farber disease (Lipogranulomatosis) is a rare, invariably fatal, inherited metabolic disorder first described by Sidney Farber in 1957 (Farber et al, 1957). Farber disease is inherited in an autosomal recessive fashion and is caused by mutations in the lysosomal acid ceramidase (ASAH1) gene. Therefore, Farber dis...