Plaque vulnerability, defined as the likelihood that a plaque would rupture, is difficult to quantify due to lack of in vivo plaque rupture data. Morphological and stress-based plaque vulnerability indices were introduced as alternatives to obtain quantitative vulnerability assessment. Correlations between these indices and key plaque features were investigated. In vivo intravascular ultrasound...

BACKGROUND Lipid accumulation product (LAP) is a novel biomarker of central lipid accumulation related to risk of diabetes and cardiovascular disease. In this study, we assessed the association of LAP with glucose homeostasis, lipid and lipid peroxidation, and subclinical systemic inflammation in diabetic patients. METHODS Thirty-nine male and 47 female type 2 diabetic patients were assessed ...

Abstract Objective: Globally, 3-5.2 percent of people suffer from diabetes which is one of the most serious metabolic disorders resulting in an increase in inflammatory biomarkers e.g. interleukin-6, tumor necrosis factor-alpha, and C-reactive protein. The aim of this study was to investigate the relationship between inflammation, oxidative stress and fasting blood glucose, lipid profile and a...

the study was designed with an aim to evaluate the protective effects of reduced glutathione on cyclophosphamide induced lipid peroxidation and also changes in cholesterol content. goat liver and white new zealand rabbit were used as lipid source for the models. lipid peroxidation study was performed by measuring the malondialdehyde, 4-hydroxy-2-nonenal, reduced glutathione and nitric oxide con...

INTRODUCTION Professional stress can damage all organs and systems of exposed workers. The aim of this study was to assess the influence of occupational stress on lipid state of exposed professional drivers in road traffic. MATERIAL AND METHODS The atherogenic risk in vehicle drivers professionally exposed to stress was assessed by measuring total cholesterol, triglycerides, HDL-cholesterol a...

BACKGROUND To evaluate real-world pharmacologic treatment of mixed dyslipidemia in patients with diabetes mellitus (DM). METHODS All commercial health plan members in a large US managed care database with complete lipid panel results (HDL-C, LDL-C, TG) between 1/1/2006 and 12/31/2006 were identified (N = 529,236). DM patients (N = 53,679) with mixed dyslipidemia were defined as having any 2 s...

background: we aimed to analyze the association between lipid variables and the extent and severity of coronary artery disease (cad) in non-diabetic turkish cypriots. methods: overall, 412 patients (mean (sd) age: 58.8 (10.5) yr, 50.1% male) who underwent diagnostic coronary angiography were included in this single-center, cross-sectional study. the friesinger index (fi) was used to assess the ...