نتایج جستجو برای: lipid derivatives

تعداد نتایج: 264212  

Journal: :European Journal of Medical Research 2010

Journal: :Chemical communications 2003
Ming-Si Wu Muthian Shanmugasundaram Chien-Hong Cheng

The CoI2(PPh3)2/Zn system effectively catalyzes the [2 + 2 + 2] ene-diyne cycloaddition of 1,6-heptadiynes with allenes in a highly regio- and chemoselective fashion to yield substituted benzene derivatives in good to excellent yields.

Journal: :Chemical communications 2010
Xianjie Fang Junyao Sun Xiaofeng Tong

A new strategy for Rh(I)-catalyzed [2+2+2] cycloadditions of 1,6-diynes with potassium (Z)-(2-bromovinyl)trifluoroborate as the third two-atom unit has been realized, which provides a facile entry to polysubstituented benzene derivatives.

Journal: :Chemical communications 2009
Hwan Myun Kim Mun Sik Seo Seung-Joon Jeon Bong Rae Cho

Hexa-substituted benzene derivatives show larger two-photon cross sections than the corresponding dipolar counterparts and the largest values of delta(max) = 2000 GM and delta(max)/MW = 2.25 GM g(-1) have been obtained with a compound having C[triple bond]C and C=C bonds in the conjugation bridge.

Journal: :Dalton transactions 2015
Jian-Jun Liu Ying-Fang Guan Yong Chen Mei-Jin Lin Chang-Cang Huang Wen-Xin Dai

We have successfully developed a new synthetic approach to modulate the electrostatic potentials of metallocavitands and thus their selective recognition towards substituted benzene derivatives via integrating two metal cations of different electronegativity into a self-assembled system.

Journal: :Acta poloniae pharmaceutica 2016
Renata Francik Jadwiga Kryczyk Sławomir Francik

Clofibric acid derivatives called fibrates, are quite commonly used lipid-lowering drugs, so it is necessary to know beneficial and adverse effects of these compounds on the body. The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has concluded that benefits of four fibrates such as: bezafibrate, ciprofibrate, fenofibrate and gemfibrozil continue outweigh thei...

Journal: :Phytochemistry 2015
Alexis Lavaud Pascal Richomme Julia Gatto Marie-Christine Aumond Cyril Poullain Marc Litaudon Ramaroson Andriantsitohaina David Guilet

Ten tocotrienol derivatives, i.e., amplexichromanols (1-10), were isolated from stem bark of Garcinia amplexicaulis Vieill. ex Pierre collected in Caledonia. The structures of the compounds 1-5 were determined to be chromanol derivatives substituted by a polyprenyl chain oxidized in terminal position. The remaining compounds 6-10 are the corresponding dimeric derivatives. Eleven known compounds...

2004
Ibolya Kocsis Krisztina Hagymási Ágnes Kéry Éva Szôke Anna Blázovics

The well known medicinal plant, Cichorium intybus L. (Asteraceae) contains dietary oligofructose compounds which have beneficial effect on carbohydrate and lipid metabolism, other compounds e.g. polyphenol type derivatives could be responsible for the antioxidant properties reported in several studies before. Male Fischer rats were kept on normal and lipid rich diet supplemented with chicory ex...

2014
Thomas M. Anderson Mary C. Clay Alexander G. Cioffi Katrina A. Diaz Grant S. Hisao Marcus D. Tuttle Andrew J. Nieuwkoop Gemma Comellas Nashrah Maryum Shu Wang Brice E. Uno Erin L. Wildeman Tamir Gonen Chad M. Rienstra Martin D. Burke

For over 50 years, amphotericin has remained the powerful but highly toxic last line of defense in treating life-threatening fungal infections in humans with minimal development of microbial resistance. Understanding how this small molecule kills yeast is thus critical for guiding development of derivatives with an improved therapeutic index and other resistance-refractory antimicrobial agents....

Journal: :The British journal of nutrition 2007
Mary C Sugden

The coordinated regulation of metabolic fuel selection is crucial to energy homeostasis. Philip Randle and his colleagues developed the fundamental concept of interplay between carbohydrate and lipid fuels in relation to the requirement for energy utilisation and storage. Their insight has fashioned current understanding of the regulation of metabolism in health and disease, as well as providin...

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