نتایج جستجو برای: lipid accumulation

تعداد نتایج: 299751  

Journal: :Archives of Physiology and Biochemistry 2021

Hydrogen sulphide (H2S), a newly identified gasotransmitter, can be endogenously produced by cystathionine gamma-lyase (CSE) in the cardiovascular system. This study investigated role of CSE/H2S system on lipid overload-induced lipotoxicity and cardiac senescence. Lipid overload rat cardiomyocyte cells (H9C2) promoted intracellular accumulation lipid, oxidative stress, mitochondrial dysfunction...

Journal: :Biochemical Society transactions 2002
C Ratledge

A small number of eukaryotic micro-organisms, the oleaginous species, can accumulate triacylglycerols as cellular storage lipids, sometimes up to 70% of the biomass. Some of these lipids, particularly those containing high proportions of polyunsaturated fatty acids of nutritional and dietary importance, are now in commercial production; these are known as single-cell oils. The biochemistry of l...

2013
Jiahua Shi Huixing Feng Jaslyn Lee Wei Ning Chen

Accumulation of intracellular lipid in oleaginous yeast cells has been studied for providing an alternative supply for energy, biofuel. Numerous studies have been conducted on increasing lipid content in oleaginous yeasts. However, few explore the mechanism of the high lipid accumulation ability of oleaginous yeast strains at the proteomics level. In this study, a time-course comparative proteo...

Journal: :International Journal of Chemical Engineering and Applications 2014

Journal: :The Journal of Japan Atherosclerosis Society 1994

2017
Prakrit V Jena Daniel Roxbury Thomas V Galassi Leila Akkari Christopher P Horoszko David B Iaea Januka Budhathoki-Uprety Nina Pipalia Abigail S Haka Jackson D Harvey Jeetain Mittal Frederick R Maxfield Johanna A Joyce Daniel A Heller

Lipid accumulation within the lumen of endolysosomal vesicles is observed in various pathologies including atherosclerosis, liver disease, neurological disorders, lysosomal storage disorders, and cancer. Current methods cannot measure lipid flux specifically within the lysosomal lumen of live cells. We developed an optical reporter, composed of a photoluminescent carbon nanotube of a single chi...

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