INTRODUCTION Leishmaniasis is endemic in more than 95 countries and is the only tropical/subtropical vector-borne disease that has been endemic in Southern Europe for decades. To the best of our knowledge, this is the first case of cutaneous leishmaniasis by Leishmania donovani in a child and the first cluster with adult cases reported in Europe. CASE PRESENTATION We describe a familial clust...

Objective(s): Protection against leishmaniasis, in the murine model, is dependent on developing a potent CD4+ mediated Th1 type response. Liposomes can be applied as immunoadjuvants to stimulate immune responses to different antigens. In the present study, it was investigated whether DOTAP liposomes having SLA and imiquimod adjuvant, can induce a Th1 response and prote...

Objective(s): Attempts to produce vaccines for leishmaniasis need adjuvants to trigger the kind of immune reaction required for protection. In this study, we examined the properties of the TLR7 agonist imiquimod, a vaccine adjuvant, making use of a live model of infection where the immune reactions could be identified prior to and following the challenge of infection. Materials and Method...

Mucocutaneous leishmaniasis in an 11-year-old girl with ataxia telangectasia Á case report L eishmaniasis is a protozoal disease caused by flagellates of the genus Leishmania and transmitted by sand fly. The reservoir hosts are humans, dogs, and rodents. It has three different morphological forms: cutaneous, mucocutaneous (MCL), and visceral. The different clinical presentations depend on the i...

congenital double lip anomaly is an infrequent developmental abnormality affecting the lips, more commonly the upper lip. 5 cases of double lip are being reported for the first time from iran and all confined to the upper lip. a new surgical excision is being introduced which is called transverse cupid bow-like elliptical incision. the previous traditional method was a simple elliptical excisio...