نتایج جستجو برای: linked retinitis pigmentosa

تعداد نتایج: 243752  

Journal: :iranian journal of public health 0
farhad adhami-moghadam 1. dept. of ophthalmology, tehran medical branch, islamic azad university , tehran, iran. elham iran-pour 2. tehran medical branch, islamic azad university , tehran, iran.

to identify mental disorders and their prevalence in patients with retinitis pigmentosa (rp).this descriptive study was carried out between january 2009 and january 2010 on 417 patients with rp, who were members of iran rp center. the necessary data were collected using questionnaires consisting two parts: the background characteristics and questions assessing the mental health and screening pe...

Journal: :Journal of medical genetics 2005
J C Booij R J Florijn J B ten Brink W Loves F Meire M J van Schooneveld P T V M de Jong A A B Bergen

OBJECTIVE To identify mutations in the AIPL1, CRB1, GUCY2D, RPE65, and RPGRIP1 genes in patients with juvenile retinitis pigmentosa. METHODS Mutation analysis was carried out in a group of 35 unrelated patients with juvenile autosomal recessive retinitis pigmentosa (ARRP), Leber's congenital amaurosis (LCA), or juvenile isolated retinitis pigmentosa (IRP), by denaturing high performance liqui...

2013
Harvey Siy Uy Pik Sha Chan Franz Marie Cruz

Unfortunately, at present, degenerative retinal diseases such as retinitis pigmentosa remains untreatable. Patients with these conditions suffer progressive visual decline resulting from continuing loss of photoreceptor cells and outer nuclear layers. However, stem cell therapy is a promising approach to restore visual function in eyes with degenerative retinal diseases such as retinitis pigmen...

2015
Ken Ogino Maho Oishi Akio Oishi Satoshi Morooka Masako Sugahara Norimoto Gotoh Masafumi Kurimoto Nagahisa Yoshimura

PURPOSE To describe the peripheral autofluorescence images and clinical features of patients with retinal dystrophy who showed radial fundus autofluorescence (FAF) at the posterior pole. METHODS The authors retrospectively reviewed pooled wide-field FAF images of 711 patients with retinal dystrophy and 56 family members. RESULTS Eleven eyes of seven women exhibited radial FAF at the posteri...

Journal: :Ophthalmic genetics 2007
Mohamed Ksantini Audrey Sénéchal Ghyslaine Humbert Bernard Arnaud Christian P Hamel

Many genes from retinoid metabolism cause retinitis pigmentosa. Peropsin, an opsin-like protein with unknown function, is specifically expressed in apical retinal pigment epithelium microvilli. Since rhodopsin and RGR, another opsin-like protein, cause retinitis pigmentosa, we used D-HPLC to screen for the peropsin gene RRH in 331 patients (288 with retinitis pigmentosa and 82 with other retina...

2005
J C Booij R J Florijn

Objective: To identify mutations in the AIPL1, CRB1, GUCY2D, RPE65, and RPGRIP1 genes in patients with juvenile retinitis pigmentosa. Methods: Mutation analysis was carried out in a group of 35 unrelated patients with juvenile autosomal recessive retinitis pigmentosa (ARRP), Leber’s congenital amaurosis (LCA), or juvenile isolated retinitis pigmentosa (IRP), by denaturing high performance liqui...

Journal: :European journal of ophthalmology 2006
L Xu L Hu K Ma J Li J B Jonas

PURPOSE To determine the prevalence of retinitis pigmentosa in the elderly Chinese population. METHODS The Beijing Eye Study is a population-based, cross-sectional cohort study and included 4439 subjects out of 5324 subjects invited to participate (response rate 83.4%) with an age of 40+ years. Readable fundus photographs were available for 4027 (90.7%) subjects. Diagnostic criteria for retin...

2014
Zi-Bing Jin Xiu-Feng Huang Ji-Neng Lv Lue Xiang Dong-Qing Li Jiangfei Chen Changjiang Huang Jinyu Wu Fan Lu Jia Qu

Retinitis pigmentosa (RP) is characterized by degeneration of the retinal photoreceptors and is the leading cause of inherited blindness worldwide. Although few genes are known to cause autosomal recessive RP (arRP), a large proportion of disease-causing genes remain to be revealed. Here we report the identification of SLC7A14, a potential cationic transporter, as a novel gene linked to arRP. U...

Journal: :Molecular cell 2007
Vladimir Pena Sunbin Liu Janusz M Bujnicki Reinhard Lührmann Markus C Wahl

Protein Prp8 interacts with several other spliceosomal proteins, snRNAs, and the pre-mRNA and thereby organizes the active site(s) of the spliceosome. The DEAD-box protein Brr2 and the GTPase Snu114 bind to the Prp8 C terminus, a region where mutations in human Prp8 are linked to the RP13 form of Retinitis pigmentosa. We show crystallographically that the C-terminal domain of yeast Prp8p exhibi...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید