We have previously shown that the LIM domains of paxillin operate as the focal adhesion (FA)-targeting motif of this protein. In the current study, we have identified the capacity of paxillin LIM2 and LIM3 to serve as binding sites for, and substrates of serine/threonine kinases. The activities of the LIM2- and LIM3-associated kinases were stimulated after adhesion of CHO.K1 cells to fibronecti...

Kinetic modeling of the bulk copolymerization of D-limonene (Lim) and n-butyl acrylate (BA) at 80 ̋C was performed using PREDICIr. Model predictions of conversion, copolymer composition and average molecular weights are compared to experimental data at five different feed compositions (BA mol fraction = 0.5 to 0.9). The model illustrates the significant effects of degradative chain transfer due...

Members of the cysteine- and glycine-rich protein family (CRP1, CRP2, and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control, and pathogenesis. Here we report the solution structure of full-length recombinant quail CRP2 as determined by multi-dimensional triple...

We present a new method for fitting peculiar velocity models to complete flux limited magnitude-redshifts catalogues, using the lumi-nosity function of the sources as a distance indicator. The method is characterized by its robustness. In particular, no assumptions are made concerning the spatial distribution of sources and their luminosity function. Moreover the inclusion of additional observa...

A linear inverse model (LIM) is used to predict Pacific (30°S–60°N) sea surface temperature anomalies (SSTAs), including the Pacific decadal oscillation (PDO). The LIM is derived from the observed simultaneous and lagged covariance statistics of 3-month running mean Pacific SSTA for the years 1951–2000. The model forecasts exhibit significant skill over much of the Pacific for two to three seas...

Purpose The purpose of this paper is to ease the methodological application critical realist multilevel research in business marketing. Although there has been plenty theoretical contributions field, it not always clear how realism can be best applied marketing settings. Accordingly, addresses gap literature. Also, calls for a conceptualization resilience, based on laminated systems. Design/met...

The authors investigate a sea surface temperature anomaly (SSTA)-only vector autoregressive (VAR) model for prediction of El Niño–Southern Oscillation (ENSO). VAR generalizes the linear inverse method (LIM) framework to incorporate an extended state vector including many months of recent prior SSTA in addition to the present state. An SSTA-only VARmodel implicitly captures subsurface forcing ob...

tributed equally to this study. Study concept and design: C. Lim and S.-L. Lim. Acquisition of data: C. Lim and S.-L. Lim. Analysis and interpretation of data: C. Lim and S.-L. Lim. Drafting of the manuscript: C. Lim and S.-L. Lim. Critical revision of the manuscript for important intellectual content: C. Lim and S.-L. Lim. Administrative, technical, and material support: C. Lim and S.-L. Lim. ...