Nifedipine (NIF), a 1,4-dihydropyridine calcium channel antagonist, undergoes photo-degradation to dehydro-nifedipine (DNIF) upon exposure to ultraviolet (UV) light and to the nitroso analogue of dehydro-nifedipine (NDNIF) when exposed to sunlight or some kinds of artificial lights. NIF photo-degradation products do not contribute to clinical activity, thus prevention of photo-degradation of NI...

Nifedipine (NIF), a 1,4-dihydropyridine calcium channel antagonist, undergoes photo-degradation to dehydro-nifedipine (DNIF) upon exposure to ultraviolet (UV) light and to the nitroso analogue of dehydro-nifedipine (NDNIF) when exposed to sunlight or some kinds of artificial lights. NIF photo-degradation products do not contribute to clinical activity, thus prevention of photo-degradation of NI...

Numerous third-generation light sources are now in a mature phase of operation, and several new sources are under construction. Submicron beam stability is being achieved routinely at many of these light sources in terms of both AC (rms 0.1 200 Hz) and DC (one week drift) motion. This level of stability is a necessary condition for the success of x-ray free-electron lasers such as the Linac Coh...

The level of photon beam stability required to meet measurement resolution goals varies from experiment to experiment, depending on experiment-specific photon phase space acceptance aperture and the sensitivity of measurement to electron beam motion within its 6-D phase space. Stability time scales range from hours to microseconds, depending on experiment sampling rate, data integration period ...

A new triazine-based covalent organic polymer (named COP-NT), which showed high catalytic activities for the degradation of acidic and basic dyes, is synthesized. Its structure characteristics were fully investigated, which featured large specific surface area, homogeneous porosity, strong visible light absorption, excellent thermal stability and semiconductor performance. The as-prepared COP-N...

In primary (light chain-associated) amyloidosis, immunoglobulin light chains deposit as amyloid fibrils in vital organs, especially the kidney. Because the kidney contains high concentrations of urea that can destabilize light chains as well as solutes such as betaine and sorbitol that serve as protein stabilizers, we investigated the effects of these solutes on in vitro amyloid fibril formatio...

nifedipine (nif), a 1,4-dihydropyridine calcium channel antagonist, undergoes photo-degradation to dehydro-nifedipine (dnif) upon exposure to ultraviolet (uv) light and to the nitroso analogue of dehydro-nifedipine (ndnif) when exposed to sunlight or some kinds of artificial lights. nif photo-degradation products do not contribute to clinical activity, thus prevention of photo-degradation of ni...