Background: Vitiligo is an acquired skin discoloration with melanocytic destruction. Vitiligo is associated with other autoimmune disorders; hence, an autoimmune etiology is among the most important theories for this disorder. The nails can be involved in numerous cutaneous or systemic non-cutaneous disorders. We have taken into consideration previous studies on nail abnormalities in vitiligo a...

A 24-year old female patient with acute lymphoblastic leukemia was treated with the induction therapy of the GIMEMA ALL protocol based on vincristine, daunorubicin, asparaginase and prednisone. In the second month of therapy, she was found to have white bands on all her fingernails. There were two bands on each fingernail (Figure), but her toenails were not affected. It was observed that the tr...

Neurophysiology studies in a 50-year-old man with slowly progressive weakness of the left upper limb revealed conduction block in the ulnar nerve above the elbow. His weakness remained stable with regular subcutaneous immunoglobulin, but he noted gradual hemibody hair depigmentation. Examination also revealed unilateral left hand leukonychia (figure). MRI of the brain and cervical spine was nor...