The Long Time Evolution Experiment. I recall the extremely interesting experiment with E. Coli, conducted by Prof. R. Lenski and his group [1, 2], and running already for more than 27 years. Among the reported results, I use the following [3]: 1. In a culture of bacteria, after 20,000 generations, around 3 × 10 single point mutations in the DNA are registered. These are local modifications of t...