localizing the optic disc (od) in retinal fundus images is of critical importance, since it is very similar to hard exudates (found in pathology) in color and brightness. because of the importance of od localization in clinical applications, many techniques have been developed. in this paper, we present the results obtained from two methods, correlation and least square, to approximate the opti...

substrates' concentration profile was studied in a porous matrix containing immobilized amyloglucosidase for glucose production. this analysis was performed by using an analytical method called least square method, and the results were compared with numerical solution. effects of effective diffusivity, michael's constant, maximum reaction rate and initial substrate concentration were studied on...