Objective(s): Oxidative stress has a pivotal role in the pathogenesis of diabetic retinopathy (DR). Juglans regia L. (JRL) leaf extract has hypoglycemic and antioxidative properties. This study aimed to determine the ameliorative effects of JRL against diabetic retinopathy. Materials and Methods: The DR rat model was generated by injection of streptozotocin (STZ). A subset of the diabetic rats ...

Background: Evidences show that Aloe vera (A. vera), Camellia sinensis, Hibiscus sabdariffa and Sophora alopecuroides may prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs). Objective: To examine the protective potential of these plants against indomethacin-induced gastric ulcer in the rat. Methods: Saline, A. vera leaf gel powder and 70% alcoholic extracts of...

In previous studies, we have shown the relaxatory effect of grape leaf (Vitis vinifera) extract on isolated ileum, uterus and aorta. In rat aorta it was revealed that the NO and endothelium are involved in the relaxation induced by grape leaf extract. The aim of present study was to investigate the effect of the Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat trachea precontracted by A...

In previous studies, we have shown the relaxatory effect of grape leaf (Vitis vinifera) extract on isolated ileum, uterus and aorta. In rat aorta it was revealed that the NO and endothelium are involved in the relaxation induced by grape leaf extract. The aim of present study was to investigate the effect of the Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat trachea precontracted by A...

An attempt was made to evaluate anti-anaemic properties of probiotic Moringa oleifera leaf extract using animal model. Twenty four male rats were randomly assigned to four groups and all the animals were given Phenylhydrazine orally to induce anaemia. Enterococcus durans was selected as probiotic supplement. Group 1 was provided with 300mg/kg of M.oleifera leaf extract. Group 2 was supplemented...

Objective: In the present study anti-inflammatory activity of ethanol extract of leaf and bark of Hugonia mystax were inveatigated. Methods: The anti-inflammatory activity of ethanol extracts leaf and bark of H. mystax were evaluated by carrageenan induced rat paw edema to determine its effect on chronic phase of inflammation models in rats. Results: Preliminary phytochemical analysis of ethano...

Zataria multiflora Boiss. is used in Iranian traditional medicine to treat gastrointestinal disorders and menrrhalgia. The inhibitory effect of this herb on rat ileum contractions is also reported. The aim of this study was to investigate the effect of Zataria multiflora Boiss. hydroalcoholic leaf extract (ZHLE) on isolated rat uterus in presence of some known uterus stimulants. Pieces of virgi...

Gymnema sylvestre Wild R.Br (family: Asclepidaceae) is a valuable medicinal plant used in folk medicine to treat diabetes, obesity, asthma etc. in India for antiquity. Diabetes mellitus is a syndrome characterized immunologically by lymphocyte apoptosis and reduced cell-mediated and humoral immunity. Modulation of immune responses to alleviate diseases has been of interest, and traditional herb...