Learning content management systems (LCMS) are web-based elearning applications that allow an instructor to deliver standards-based learning content to communities of learners. Despite the high popularity of these systems, they tend to have minimal collaborative navigation and awareness features, and students often find themselves learning in a vacuum without a sense of what the rest of the lea...

Building semantics concepts into the learning tools and utilities will open the road for the next generation of the Learning Content Management System (LCMS). We propose here to name this new learning environment the Semantic LCMS. This paper presents some reflections about how the semantic kernel of an SLCMS could be viewed. This semantic kernel is in close relation with a set of primitive rul...

Biomedical Research Models, Inc. In vivo receptor occupancy (RO) is a valuable tool used in preclinical drug development to confirm target engagement and faci litate selection of compounds for further development. We have been using radioligand-based RO as means of measuring target engagement in the rat brain. In this approach, compounds of interest are peripherally injected prior to intravenou...

BACKGROUND Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analysis requires expertise in computational programming. Here, we describe open-access web-based appli...

Various instrument types and LC-MS approaches have been explored in an attempt to develop a comprehensive analysis method for detecting and definitely identifying as many compounds as possible in a single run. However, everyday analyses often require the detection of a defined set of substances (for example, hypnotics in cases of drugfacilitated assault (DFA). The aim of this project was to dev...

Now a day’s most of the educational centre (universities, institutes, colleges and schools) are using some eLearning tools as an integral part of their learning systems; to enhance their traditional learning systems or to use an alternative approach for virtual learning environment. These tools may base on content management or learning content management. Recently a composition of Learning Man...

Samples of young, outer surfaces of brucite-carbonate deposits from the ultramafic-hosted Lost City hydrothermal field were analyzed for DNA and lipid biomarker distributions and for carbon and hydrogen stable isotope compositions of the lipids. Methane-cycling archaeal communities, notably the Lost City Methanosarcinales (LCMS) phylotype, are specifically addressed. Lost City is unlike all oth...

the streptomycetes sp. scbt strain gen bank accession number eu143270 isolated from the rhizosphere soil of medicinal plants was collected from the kolli hills of tamil nadu, india. the strain streptomyces is designated as school of chemical and biotechnology (scbt), capable of inhibiting the growth of a wide range of gram-negative and gram-positive bacteria. an almost complete 16s rrna gene se...