CONTEXT Sulfur mustard (SM) was used during the Iraq-Iran war (1980-1988). Exposed veterans continue to suffer from its ocular, skin, and respiratory complications. OBJECTIVE We aimed to evaluate associations between early (at the time of acute exposure) and decades later skin manifestations in individuals with severe ophthalmologic complications secondary to sulfur mustard exposure. MATERI...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

background : alzheimer's disease (ad) is one of the most common problems for old peoples. etiology of ad is not clear, but genetic factors play a major role in determining a person's risk to develop ad. twin and family studies con-firm that ad has a genetic basis.ad genetics has been split into two broad categories: early-onset and late-onset. eo-ad cases are inherited in an autosomal dominant ...

lipoid proteinosis (lp) is a rare autosomal recessive disease characterized by the deposition of an amorphous hyaline material in the skin, mucosa and viscera. the classic manifestation is onset in infancy with a hoarse cry due to laryngeal infiltration. skin and mucous changes develope, and the disease follows a slowly progressive course. in this case report, a 49 year-old man presented with a...

background sweet's syndrome which is characterized by fever and acute onset of skin lesions is in many times associated with other conditions including renal disease. type of association and true rate is not yet clear. case report we report a woman with end stage renal disease and peritonitis who eveloped sweet's syndrome.

BACKGROUND Posttransplantation lymphoproliferative disorders (PTLDs) are lymphoid proliferations that can develop in recipients of solid organ or allogeneic bone marrow transplants. They are clinically and pathologically heterogeneous and range from polyclonal hyperplastic lesions to malignant lymphomas. Although extranodal involvement in PTLD is common, cutaneous presentation is rare, with onl...

Background: Pemphigus is an autoimmune disease characterized with intra-epidermal cleavage. Objective: The aim of this study was to examine the clinical and epidemiologic features of pemphigus in Khouzestan province, southwest Iran. Patients and Methods: All new cases of pemphigus admitted in the department of dermatology, Sina Hospital, Ahwaz University from October 1990 to September 1999 were...

Inflammatory linear verrucous epidermal nevus (ILVEN) is a unilateral skin disorder which usually manifests in infancy or childhood. Female predominance, frequent leg involvement, pruritus, resistance to treatment, and a psoriasiform histologic pattern are other common characteristics of this disease. Atypical presentations of ILVEN have been described and include late onset in life, wide...

argas reflexus is considered obligate blood feeder that may cause skin redness and local swelling. for histopathological evaluation of biting site, pigeons were used as natural host species in this study. adult ticks were collected from urmia, north-west of iran and kept in a desiccator before their use in the experiment. sixteen pigeons were infested experimentally and were divided into 4 grou...

Background: Vitiligo is a common skin disease that clinically presents as depigmented macules due to destruction of melanocytes. Although the cause is unknown, various theories such as autoimmune, autodestruct and neural hypotheses have been proposed. Objective: The objective of this study was to evaluate clinical picture of vitiligo in Isfahan, Iran. Patients and Methods: In a descriptive stud...