Copper Bromide Laser vs Triple-Combination Cream for the Treatment ofMelasma: A Randomized Clinical Trial Recent studies have suggested the potential effectiveness of targeting the vascular component of melasma.1-4 The copper bromide laser (Dual Yellow;Norseld) is a laserwith a concomitant-outputdual-wavelength light source comprising90%yellowlightat578nm,whichtargetsvascular lesions,and10% gre...

We report a generic approach for targeting proteins into micropatterns by in situ laser lithography. To this end, we have designed a photocleavable oligohistidine peptide for caging tris(nitrilo triacetic acid) (tris-NTA) groups on surfaces by multivalent interactions. Local photofragmentation of the peptide by UV illumination through a photomask or by a confocal laser beam uncages tris-NTA, th...

multifunctional nanomaterials showed graet advantages in drug delivery. folic acid (fa) binding protein, a glycosyl phosphatidyl inositol anchored cell surface receptor for folate, is overexpressed in several human tumors, whereas it is highly restricted in normal tissues. therefore, in this study, fa, polyethylene glycol (peg), and fe3o4 nanoparticles multifunctionalized short multiwall carbon...

The FCS Laser-Hardened Vision STO seeks to develop an electro-optic targeting vision system that utilizes a combination of nonlinear and sacrificial materials to provide protection from damage by frequency-agile battlefield lasers at both long and short range. Evidently, the selection of sensor protection technologies for incorporation into the final targeting system will be based on their opti...

Carbon nanotubes (CNTs) are emerging versatile tools in nanomedicine applications, particularly in the field of cancer targeting. Due to diverse surface chemistry and unique thermal properties, CNTs can act as strong optical absorbers in near infrared light where biological systems prove to be highly transparent. The process of laser-mediated ablation of cancer cells marked with biofunctionaliz...

We numerically show that a laser that would suffer from coherence collapse if precautions were not taken can be made to operate with a small linewidth and a stable maximum output power by application of a new dynamic targeting technique.

Laser ablation is gaining acceptance as a cancer treatment technique because of its localized energy delivery to the tumorous tissue. The combination laser with nanoparticles allows for more precise targeting ablative area less damage adjacent healthy Nevertheless, heat tissue still potential concern. Therefore, mathematical modeling laser-tissue interactions necessary part clinical planning. I...

Diabetic retinopathy (DR) is a severe sight-threatening complication of diabetes mellitus. Retinal laser photocoagulation, antivascular endothelial growth factors, steroid therapy, and pars plana vitrectomy are now used extensively to treat advanced stages of diabetic retinopathy. Currently, diagnostic devices like ultrawide field fundus fluorescein angiography and the improvement of optical co...