Background: Lactic acidosis in cardiac surgical patients is a manifestation of systemic inflammation and excess pro-inflammatory cytokine production. This investigation was designed to integrate basic concepts about lactate acidosis with a clinically used of serum lactate in patients under coronary artery bypass surgery (CABG) by on pump method. Methods: From August to September 2012, 15 patie...

Background: Hodgkin’s disease (HD) is a neoplastic disease originating in lymphoid tissue, which spreads to lymphoid structures and ultimately nonlymphoid tissues. Lactate Dehydrogenase and Alkaline Phosphatase are increased in blood following membrane cell damage. The aim of this study was to compare Lactate Dehydrogenase and Alkaline Phosphatase levels in children in different stages of Hodg...

background: acanthosis nigricans (an) is a brown to black, velvety hyperpigmentation of the skin that usually involves cutaneous folds. treatment of an is important regarding cosmetic reasons and various therapeutic modalities have been used for these purposes. the goal of this study was to compare the effectiveness of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate for tre...

conclusions based on the findings, the mortality rate was 22.9% among poisoned patients with an elevated serum lactate level. we can conclude that mortality is associated with toxicants, but not the occurrence of vap; in fact, vap scenarios do not elevate serum lactate level. background lactate level is known to increase among the majority of patients with toxicity. this study aimed to determin...

Background: Persistently infected cells by herpesvirus (HSV, CMV, EBV) and their dysfunction are associated with different disorders. The immune and endocrine systems are involved in pathogenesis of herpesvirus infection. Changes of IFN-γ, IL-4, DHEAS and cortisol level are a part of the regulatory mechanisms of the immune and endocrine system responses in persistent herpesvirus infection. Obje...

In glucose (Glc) metabolism, lactate dehydrogenase (LDH) functions by changing pyruvate into lactate. Lactate release is induced viacell death, suggesting to disease caused virus or pulmonary deterioration, such as inflammation of the lung triggered severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). A satisfactory evidence exists binding elevated levels development coronavirus 2019 (...