Lacrimal glands of mammals synthesise and secrete an aqueous solution in which different chemical substances are present i.e. protein and mucosubstances. The objective of current study was to determine of mucopolysachharides of camel lacrimal glands. Ten pairs of dorsal lacrimal glands, from ten adult camels were examined for normal histological and histochemical findings at the Mashhad abattoi...

Orbital involvement in systemic sarcoidosis is a rare condition. We report a case of orbital sarcoidosis with bilaterally huge lacrimal gland involvement as the initial manifestation of systemic sarcoidosis. A 20-year-old woman admitted the ophthalmology department with progressive bilateral upper eyelid swelling for 6 months. The only pathologic finding was the presence of bilateral, symmetric...

HASHIMOTO (1912) remarked on the similarity of the form of thyroiditis, described by him and now known by his name, to the lesions of Mikulicz's disease, which include a chronic inflammatory reaction in the lacrimal glands. Only recently, however, has evidence accumulated of a true association between non-infective chronic inflammatory lesions of the thyroid and lacrimal glands (Anderson, Gray,...

CASE REPORT We report the case of a 48 year-old male with bilateral involvement of the salivary and lacrimal glands, which was diagnosed as Mikulicz's disease by incisional biopsy of the affected lacrimal glands, which was completely resolved after corticosteroid treatment. DISCUSSION Sclerosing sialadenitis and/or dacryoadenitis are chronic inflammatory diseases that are currently classified...

OBJECTIVE To study the effects of lacrimal gland removal on basal and reflex tear production and on the ocular surface in the squirrel monkey. METHODS Unilateral main lacrimal gland removal in 6 squirrel monkeys was followed by Schirmer testing, slit-lamp examination with fluorescein, and collection of basal and reflex (stimulated) tears for analysis of tear protein spectra between 0 and 20 k...

Sjogren's syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration into lacrimal and salivary glands leading to symptomatic dry eyes and mouth. Immunohistological studies have clarified that the majority of infiltrating lymphocytes around the lacrimal glands and labial salivary glands are CD4 positive alphabeta T cells. To analyze the pathogenesis of T cells infiltrating...

A 40-year-old woman presented with vague headaches and blurred vision. Contrast-enhanced magnetic resonance imaging of the brain revealed bilaterally symmetrical diffuse enlargement of the lacrimal glands. A fine needle biopsy of the lacrimal gland was consistent with sarcoidosis. Although, isolated lacrimal gland involvement is rare, it may be the initial clinical presentation of sarcoidosis, ...

PURPOSE The accessory lacrimal glands are assumed to contribute to the production of tear fluid, but little is known about their function. The goal of this study was to conduct an analysis of gene expression by glands of Wolfring that would provide a more complete picture of the function of these glands. METHODS Glands of Wolfring were isolated from frozen sections of human eyelids by laser m...

LEUKAEMIC infiltration of the lacrimal sac is rare (Duke-Elder, 1952) and dacryocystitis due to leukaemic involvement of the sac has seldom been reported (Stokes, 1938; Busina, 1950). The number of cases recorded is increased when the reports of Sulzer and Duclos (1906), Pascheff (1927), and Weve (1928) are considered, but these authors described lymphomata of the sac without the typical blood ...

Many accessory lacrimal glands can be found along the inner surface of the eyelids. A variable number of thin-walled excretory ducts, blood vessels, lymphatics, and nerves pass from the main orbital gland into these accessory lacrimal glands. The ducts continue downward, and about 12 of them empty into the conjunctival fornix approximately 5 mm above the superior margin of the upper tarsus. Bec...