نتایج جستجو برای: l31
تعداد نتایج: 143 فیلتر نتایج به سال:
Autoimmune peripheral neuropathies such as Guillain-Barre Syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) affect millions of people worldwide. Despite significant advances in understanding the pathology, the molecular and cellular mechanisms of immune-mediated neuropathies remain elusive. T lymphocytes definitely play an important role in disease pathogenesis and CD4...
BACKGROUND The aim of this study was to evaluate the efficacy of daclatasvir plus asunaprevir therapy in patients infected with hepatitis C virus and determine its relevance to resistant variants. METHODS A total of 629 consecutive patients infected with hepatitis C virus genotype 1 were assessed. Daclatasvir (60 mg/day) plus asunaprevir (200 mg/day) was given for 24 weeks. The virological re...
We discuss economic rationales behind peering decisions in the Internet. In the first part of the paper we analyze the decision about a bilateral peering agreement between two commercial Internet service providers (ISPs) who are in Cournot competition. In the second part we discuss multilateral peering between commercial ISPs and an academic research network (ARN). The latter is organized as cl...
ABSTRACT Private organizations that produce public goods often receive offers for funding from large donors who seek to influence the nature of produced. We consider a model in which potential donor creates commitment problem organization sense that, an ex ante perspective, sets price too low given opportunity cost. Our analysis identifies determinants likelihood and assesses various mechanisms...
This article explains why the collective determination of interchange fees in payment platforms and in ATM networks can lead to ine¢ ciencies in the substitution between payment cards and cash. If the issuers are ATM owners, I show that the pro t maximising interchange fees reect the trade-o¤ that banks make between the pro ts on foreign withdrawals and the possibility to save the costs of cas...
Fundraising interventions may lift donations and/or shift their composition and timing. Using data rich in both the charity space time dimensions, we find that major fundraising appeals to appeal this increase is not offset by lower later time. Strikingly, also forward-shift other (nonappeal) charities are later. To understand these response patterns, introduce a two-period, two-charity “ lift-...
Theoretical and empirical models explore the effects of a gender equity regulation imposed on an athletic director at a nonprofit university. The behavioral model predicts a decrease in the total number of sports teams and a net decrease in the number of men’s teams, suggesting that the regulation has unintended consequences. The empirical analysis confirms the theory and identifies the size an...
А number of ribosomal proteins inEscherichia coliundergo posttranslational modifications. Six ribosomal proteins are methylated (S11, L3, L11, L7/L12, L16, and L33), three proteins are acetylated (S5, S18, and L7), and protein S12 is methylthiolated. Extra amino acid residues are added to protein S6. С-terminal amino acid residues are partially removed from protein L31. The functional significa...
Social enterprises have attracted increased attention from both researchers and practitioners around the world. In social enterprise context, scaling impact is considered main currency or key performance metric. Two overarching strategies are organizational growth strategy ecosystem strategy. However, to date, little cumulative knowledge exists on these two strategies. To address this issue, ar...
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