Non-steroidal anti-inflammatory drugs (NSAIDs) have been used to treat various ailments for over 100 years. As a class, these drugs possess anti-inflammatory, anti-allergy, analgesic and antipyretic activity. A series of benzothiazolylamides has been synthesized and tested for antiinflammatory activity. Basic NSAIDs are gaining interest because of their improved biological properties with the a...

Four different hydrocolloids, carageenan, carboxymethyl cellulose, guar gum and xanthan were administered at four different levels of substitution, 0.25, 0.5, 0.75 and 1.0% to 7.0% (w/w) fennel fortified bread to study the effects of hydrocolloids as texture improver. Physical properties like loaf weight were mostly unchanged while addition of hydrocolloid seems to have a positive effect on loa...

1. Assistant Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. 2. Assistant Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. 3. Professor of pharmacology, United Medical & Dental College, Karachi 4. Professor of Pharmacology, Bahria University Medical & Dental College, Karachi. ABSTRACT... Objective: To evaluate anti-inflammatory acti...

Symplocos racemosa Roxb bark belongs to the family: Symplocaceae. In Ayurveda it is known as Lodhra. The bark was collected and dried for four days under sun and powdered. It was extracted with different solvents ethanol, methanol and ethyl acetate by soxhlet hot extraction process. Preliminary phytochemical analysis was carried out for different extracts. It was found that saponin glycosides a...

ABTRACT Thiazolidinedione ligands for the gamma subtype of peroxisome proliferator-activated receptors (PPARγ), widely used to treat type 2 diabetes mellitus, have been shown to have anti-inflammatory action in some animal models. This study is carried out to evaluate the anti-inflammatory activity of rosiglitazone & Pioglitazone with the standard drug Diclofenac sodium (NSAID). Carageenan is u...

Symplocos racemosa Roxb bark belongs to the family: Symplocaceae. In Ayurveda it is known as Lodhra. The bark was collected and dried for four days under sun and powdered. It was extracted with different solvents ethanol, methanol and ethyl acetate by soxhlet hot extraction process. Preliminary phytochemical analysis was carried out for different extracts. It was found that saponin glycosides a...

The purpose of this study was to obtain an amorphous system with minimum unit operations that will prevent recrystallization of amorphous drugs since preparation, during processing (compression) and further storage. Amorphous celecoxib, solid dispersion (SD) of celecoxib with polyvinyl pyrrollidone (PVP) and co-precipitate with PVP and carrageenan (CAR) in different ratios were prepared by the ...

The effect of using some stabilizers on the viscosity, over-run, melting characteristics and sensory properties of frozen yogurt was investigated in this study. The ice cream mix in all groups was 10% fat, 13% sucrose, 13% MSNF (milk non-fat solids). stabilizers that were tried were Panisol ex (P), salab (s) and a mix of stabilizers and emulsifiers (M) include (sodium alginate (0.23%), guar (0....

There is a high prevalence of usage of complementary and alternative medicines for the treatment of bronchial asthma which is considered as a chronic inflammatory disorder of the airways. Abutilon indicum G. Don. (Fam: Malvaceae) is abundantly found as a weed throughout the tropical parts of India. It is reported to have anti-inflammatory action and is used internally for inflammation of the bl...

Mirabilis Jalapa Linn. is a widely used traditional medicine in many parts of the world for the treatment of various diseases viz. virus inhibitory activity, anti tumour activity. It is claimed in traditional medicine that the leaves of the plant are used in the treatment of inflammation. In the present study, the total alcoholic extract and successive petroleum ether fractions of leaves of Mir...