In this section, R denotes a ring with identity I. We study conditions under which I - Aλ and I - Bλ are left coprime or right coprime, where A, B ∈ R. As applications, we get sufficient conditions under which the Kneading determinant of a finite rank pair of operators on an infinite dimensional space is rational.

Paracetamol (PCM) is a non-steroidal anti-inflammatory drug (NSAID), sparingly soluble and bitter in taste. It is widely used as an analgesic and antipyretic. Solid dispersion of drug with different polymers was attempted to improve solubility of paracetamol.The aim of this study was to prepare, characterize and compare solid dispersions of poorly water soluble non-steroidal anti-inflammatory d...

A twin-screw granulator (TSG), a promising equipment for continuous high shear wet granulation (HSWG), achieves the desired level of mixing by a combination of the appropriate screw configuration and a suitable set of process settings (e.g. feed rate, screw speed, etc.), thus producing a certain granule size and shape distribution (GSSD). However, the primary sizing and shaping mechanism behind...

The aim of the present study was to increase the solubility of a poorly water soluble BCS class II drug, valsartan. Liquisolid technology and solid dispersion by kneading method were techniques used to improve the solubility of the drug by using non-volatile solvents and some hydrophilic carriers. Liquisolid compacts were prepared by dissolving the drug in suitable non volatile solvents. The va...

In this article we report on work concerned with the three-dimensional numerical simulation of dough mixing that arises in the food processing industry. Two dough mixers at various rotation speeds are studied, one with one stirrer and the other with two stirrers. Various types of fluid models are incorporated in this work. Numerical simulations are based on three dimensions in the cylindrical c...